Evidence map›Paper›PMID 42474738›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Effect of vicryl 7 - 0 suturing versus diathermy closure on the ocular surface after small-gauge vitrectomy: a prospective randomized study.

Maura Mancini, Gregorio Lo Giudice, Antonio Valastro, Claudio Brancato, Alessandra Mancini, Paola Palino, Laura De Luca, Pasquale Aragona, Alessandro Meduri

Abstract read
PubMed Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maura ManciniDepartment of Biomedical Sciences, Ophthalmology Clinic, University of Messina, Messina, Italy.
Gregorio Lo GiudiceDepartment of Ophthalmology, ARNAS Civico Hospital, Palermo, Italy.
Antonio ValastroOphthalmology Department, Beauregard Hospital, Azienda USL della Valle d'Aosta Via L. Vaccari 5, Aosta, 11100, Italy. antonio.valastro2@gmail.com.
Claudio BrancatoDepartment of Ophthalmology, ARNAS Civico Hospital, Palermo, Italy.
Alessandra ManciniDepartment of Ophthalmology, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Paola PalinoDepartment of Biomedical Sciences, Ophthalmology Clinic, University of Messina, Messina, Italy.
Laura De LucaDepartment of Biomedical Sciences, Ophthalmology Clinic, University of Messina, Messina, Italy.
Pasquale AragonaDepartment of Biomedical Sciences, Ophthalmology Clinic, University of Messina, Messina, Italy.
Alessandro MeduriDepartment of Biomedical Sciences, Ophthalmology Clinic, University of Messina, Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the impact of routine 7 - 0 Vicryl suturing versus external bipolar diathermy for 23-gauge sclerotomy closure on postoperative ocular-surface integrity and patient discomfort.

methodsThis prospective, multicenter randomized study included adults undergoing primary 23-gauge transconjunctival pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment repair or macular surgery, without combined phacoemulsification. Patients were randomized to sclerotomy closure with a single 7 - 0 polyglactin (Vicryl) suture at each port or to external bipolar diathermy sealing. Ocular-surface assessment was performed with Keratograph

resultsFifty-four patients were analyzed (Vicryl n = 26; diathermy n = 28). Both groups showed an early postoperative reduction in NIBUT and increased redness, but diathermy demonstrated faster recovery. At 3 months, NIBUT was higher with diathermy (7.5 ± 1.4 s) than Vicryl (5.0 ± 1.3 s; p < 0.001), with lower bulbar redness (1.0 ± 0.3 vs. 1.9 ± 0.4; p < 0.001) and lower VAS discomfort (3.0 ± 1.0 vs. 5.0 ± 1.1; p < 0.001). No persistent postoperative hypotony occurred.

conclusionIn primary 23-gauge PPV with routine port closure, external bipolar diathermy was associated with superior ocular-surface recovery and lower discomfort compared with 7 - 0 Vicryl suturing through 3 months, with reassuring short-term IOP outcomes.

Indexed as

DiathermyNon-invasive tear break-up timeOcular surfacePars plana vitrectomySclerotomy closureVicryl

Identifiers

PMID42474738

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.