Evidence map›Paper›PMID 42474717›Full record

ArticleAbdominal radiology (New York)2026

Abbreviated T2w-only pelvic MRI for local tumor staging of cervical cancer: a pragmatic approach for time-critical and resource-limited settings.

Moritz T Winkelmann, Alan Bareiss, Johanna T Winkelmann, Sascha Hoffmann, Heike Preibsch, Konstantin Nikolaou, Christina B Walter, Felix Peisen

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Article in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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8 authors.

Moritz T WinkelmannDepartment of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany. moritz.winkelmann@med.uni-tuebingen.de.ORCID https://orcid.org/0000-0002-3945-3686
Alan BareissDepartment of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Johanna T WinkelmannDepartment of Women's Health, University Hospital Tuebingen, Tuebingen, Germany.
Sascha HoffmannDepartment of Women's Health, University Hospital Tuebingen, Tuebingen, Germany.
Heike PreibschDepartment of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Konstantin NikolaouDepartment of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Christina B WalterDepartment of Women's Health, University Hospital Tuebingen, Tuebingen, Germany.
Felix PeisenDepartment of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Tuebingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the diagnostic performance and inter-reader reliability of an abbreviated non-angulated three-plane T2-weighted pelvic MRI protocol for assessing local staging key parameters in cervical cancer.

methodsIn this retrospective single-center study, 47 patients with cervical cancer who underwent pelvic MRI between January 2023 and December 2024 were included. MRI was performed on a 1.5-T system using a simplified protocol; image interpretation was restricted to axial, sagittal, and coronal T2-weighted turbo spin-echo sequences. Two board-certified radiologists (one subspecialized in gynecological imaging, one general radiologist) independently assessed tumor size, parametrial invasion, vaginal involvement, and local T stage. A composite reference standard consisting of examination under anaesthesia, laparoscopic staging, and histopathology was used. Diagnostic performance metrics and inter-reader agreement (Cohen's κ, ICC) were calculated.

resultsParametrial invasion was detected with high diagnostic accuracy, with a mean sensitivity of 94.0% and specificity of 88.6% across both readers. For vaginal invasion, mean sensitivity and specificity were 95.5% and 96.0%, respectively. Inter-reader agreement was excellent for tumor size measurements (ICC 0.946-0.992) and high for categorical variables categorical variables (κ = 0.828 for parametrial and 0.915 for vaginal invasion). Agreement between MRI and the reference standard for tumor size was good, with mean differences of 3.1-4.8 mm. The abbreviated protocol corresponded to an acquisition time of approximately 13 min compared to 21 min for the simplified institutional protocol and 30-45 min for standard multiparametric MRI.

conclusionA non-angulated three-plane T2-weighted pelvic MRI protocol provides high diagnostic accuracy and inter-reader agreement for assessing local staging key parameters in early-stage to locally advanced cervical cancer without bladder or rectal involvement and may represent a feasible alternative in time-constrained or resource-limited settings.

Indexed as

Abbreviated MRI protocolDiagnostic accuracyMagnetic resonance imagingNeoplasm stagingT2-weighted imagingUterine cervical cancer

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.