ArticleApplied biochemistry and biotechnology2026
Biogenic Carbon Dots From Hyaluronic Acid and Opuntia humifusa (Eastern Prickly Pear Cactus) for Enhanced Antioxidant Protection and Skin Hydration: An In Vitro Study.
Article in Applied biochemistry and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The growing demand for safe, naturally derived active ingredients in cosmetic and dermatological formulations has accelerated interest in green nanomaterials with multifunctional skin-protective properties. This study presents the microwave-assisted synthesis and comparative evaluation of carbon dots (CDs) derived from hyaluronic acid (HA) and eastern prickly pear cactus (Opuntia humifusa (O. humifusa)) for their moisturizing and antioxidant properties. Both CDs exhibited strong UV absorption at 264 nm and characteristic blue photoluminescence around 450 nm, indicating their potential as UV-protective cosmetic nanomaterials. In antioxidant assays, O. humifusa-CD exhibited significantly higher radical scavenging activity (p < 0.05), with an estimated ABTS IC₅₀ value of 585 µg/mL compared with 710 µg/mL for HA-CD. Similarly, both CDs showed significant intracellular ROS scavenging activity in H
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