Evidence map›Paper›PMID 42474673›Full record

ArticleInternational urology and nephrology2026

Clinical outcomes of thulium fiber laser versus holmium:YAG laser during pediatric retrograde ıntrarenal surgery: a multicenter cohort study.

Burak Özçift, Uygar Miçoogulları

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Article in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

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2 authors.

Burak ÖzçiftDepartment of Pediatric Urology, Health Sciences University, Izmir Dr. Behcet Uz Child Diseases and Surgery Training and Research Hospital, İsmet Kaptan Mh. Sezer Doğan Sok. No: 11 Konak, Izmir, Turkey. burakozcift@gmail.com.ORCID https://orcid.org/0000-0001-8474-2308
Uygar MiçoogullarıDepartment of Urology, Izmir Can Hospital, Izmir, Turkey.ORCID http://orcid.org/0000-0003-4729-6104

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe thulium fiber laser (TFL) is a new-generation laser technology that has been increasingly used in endourology in recent years. However, data on the use of TFL in the treatment of pediatric kidney stones are limited. The aim of this study was to compare the efficacy and safety of thulium fiber laser (TFL) and Holmium: Yttrium Aluminum Garnet (Ho:YAG) laser in children undergoing retrograde intrarenal surgery (RIRS) for a solitary renal stone measuring 10-20 mm. MATERIALS AND

methodsPediatric patients (< 18 years) with a solitary renal stone measuring 10-20 mm who underwent RIRS at two tertiary referral centers between January 2020 and March 2026 were retrospectively reviewed. Patients were divided into two groups based on the laser technology used: Ho:YAG and TFL. Ho:YAG lithotripsy was predominantly performed using fragmentation strategy, whereas TFL was mainly used in dusting mode. The primary endpoint was the stone-free rate (SFR), as assessed by ultrasound at the third postoperative month. Secondary endpoints included operative time, fluoroscopy time, intraoperative stone retropulsion, the need for reintervention, length of hospital stay, and complications according to the Clavien-Dindo classification.

resultsA total of 74 patients were included in the study. Forty-eight patients were treated with Ho:YAG, and 26 with TFL. The groups were comparable in terms of age, sex, body mass index, stone size, stone density, and stone location. Operative time was significantly shorter in the TFL group than in the Ho:YAG group (64.0 ± 28.35 vs. 80.0 ± 30.17 min, p = 0.028). Intraoperative stone retropulsion occurred significantly less frequently in the TFL group (11.5% vs. 35.4%, p = 0.031). The 3-month stone-free rate was 92.3% in the TFL group and 85.4% in the Ho:YAG group, with no significant difference between the groups (p = 0.486). No significant differences were found between the groups in terms of fluoroscopy time, reintervention rate, and length of hospital stay. Complication rates were similar, and no Clavien-Dindo grade IV or V complications were observed in either group.

conclusionThese findings suggest that TFL may represent a safe and effective alternative to the Ho:YAG laser in pediatric RIRS. However, further prospective multicenter studies using standardized laser settings are warranted to validate these findings.

Indexed as

Flexible ureteroscopyHolmium:YAG laserPediatric urolithiasisRenal stoneRetrograde intrarenal surgeryThulium fiber laser

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.