Evidence map›Paper›PMID 42474601›Full record

ArticleAnnals of biomedical engineering2026

Exploratory Assessment of Robotic Ankle Foot Orthosis Stiffness and Neutral Angle on Stair Ambulation in Individuals with Cerebral Palsy.

Samuel Hopkins, Connor Gaudette, Maria Jose Silvetti, Zachary F Lerner

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Article in Annals of biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samuel HopkinsDepartment of Mechanical Engineering, Northern Arizona University, Sanghi College of Engineering, Flagstaff, AZ, USA. ssh252@nau.edu.ORCID http://orcid.org/0009-0005-6033-7304
Connor GaudetteDepartment of Mechanical Engineering, Northern Arizona University, Sanghi College of Engineering, Flagstaff, AZ, USA.
Maria Jose SilvettiDepartment of Mechanical Engineering, Northern Arizona University, Sanghi College of Engineering, Flagstaff, AZ, USA.
Zachary F LernerDepartment of Mechanical Engineering, Northern Arizona University, Sanghi College of Engineering, Flagstaff, AZ, USA.ORCID http://orcid.org/0000-0002-7359-436X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIndividuals who wear Ankle Foot Orthoses (AFOs) express a desire for adaptability and improved stair ambulation. This exploratory study examined how the stiffness and neutral angle of a robotic AFO influence stair ambulation and preference in spastic cerebral palsy (CP) and compared robotic AFOs, solid AFOs, and shoes alone.

methodsSeven individuals with spastic CP completed modified Timed-Up-and-Down-Stairs (TUDS) tests under nine robotic AFO stiffness-neutral angle configurations, solid AFOs, and shoes alone. Outcomes included TUDS time, ankle kinematics, soleus and vastus lateralis activity, exertion, balance confidence, trunk instability, stiffness preference, and device power and torque. Mixed effects modeling assessed the effects of stiffness and neutral angle. Stiffness preference was evaluated during level walking, stair ascent, and descent. Repeated measures ANOVA compared robotic AFOs, solid AFOs, and shoes alone.

resultsIncreased stiffness and more plantarflexed neutral angles decreased peak dorsiflexion (p < 0.05) and increased peak torque (p < 0.05). Few other outcomes were affected. Four of seven participants preferred low stiffness across all tasks. Robotic AFOs performed better than solid AFOs, by decreasing TUDs time (- 27%, d = - 0.66, p < 0.05) and increasing confidence (49%, d = 0.92, p < 0.05) in descent, but not better than shoes alone. During stair ascent, the only difference between the AFOs and shoes was a reduction in soleus activity between solid AFOs and shoes alone.

conclusionRobotic AFO configuration influences stair descent and may improve descent speed and confidence over solid AFOs in a limited sample of spastic CP.

Indexed as

Assistive devicesBiomechanicsLocomotionMotor disability

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.