ArticleJournal of robotic surgery2026
Robotic-assisted radical prostatectomy for large-volume prostates (>100 mL): perioperative, functional, and oncologic outcomes from a 5-year multicenter cohort.
Article in Journal of robotic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Large prostate volume (> 100 mL) remains a technical challenge during robot-assisted radical prostatectomy (RARP), with limited long-term outcome data available in contemporary series. To evaluate perioperative, functional, and oncologic outcomes following RARP in patients with large-volume prostate cancer. A retrospective multicenter cohort study was performed including 201 consecutive patients with prostate volume > 100 mL who underwent RARP between January 2017 and December 2021, with follow-up extending through December 2023. The primary endpoint was biochemical recurrence-free survival (BCRFS). Secondary endpoints included overall survival (OS), cancer-specific survival (CSS), perioperative outcomes, urinary continence recovery, and erectile function recovery. Kaplan-Meier analyses, multivariable Cox proportional hazards regression, and logistic regression analyses were performed. Median prostate volume was 121 mL (IQR 108-142), and median follow-up was 58 months (IQR 46-60). Mean operative time was 121 ± 28 min, while estimated blood loss was 152 ± 70 mL. Major complications (Clavien-Dindo ≥ III) occurred in 4.5% of patients. Positive surgical margins were observed in 15.9%, and pT3 disease was identified in 46.2%. Five-year BCRFS, OS, and CSS were 79.8% and 95.8%, respectively. Urinary continence recovery reached 84.1% at 12 months and 90.6% at 5 years. Erectile function recovery among patients undergoing bilateral nerve-sparing was 48.6% at 12 months and 62.3% at 5 years. On multivariable analysis, Gleason score ≥ 8 (HR 2.63, p < 0.001), pT3 stage (HR 3.02, p < 0.001), and positive surgical margins (HR 2.11, p = 0.01) independently predicted biochemical recurrence. Bilateral nerve-sparing independently predicted improved continence recovery (OR 1.82, p = 0.02). RARP in patients with large-volume prostates is safe and oncologically effective, with favorable long-term functional outcomes. Tumor biology rather than prostate size appears to be the principal determinant of oncologic outcomes.
Indexed as
Identifiers
42474561What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.