Evidence map›Paper›PMID 42474318›Full record

ArticleJournal of bacteriology2026

Short-chain fatty acids activate the glutamate-dependent acid resistance system via the tRNA-modifying Mnm pathway in

Lingyun Guo, Sophie Brameyer, Nicola Victoria Hoesch, Serena Schwenkert, Sebastián Riquelme-Barrios, Sabine Peschek, Max Berg, Manh Dat Hoang, Karin Kleigrewe, Stefanie Kaiser and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lingyun GuoFaculty of Biology, Microbiology, Ludwig-Maximilians-University of Munich, Martinsried, Germany.
Sophie BrameyerFaculty of Biology, Microbiology, Ludwig-Maximilians-University of Munich, Martinsried, Germany.
Nicola Victoria HoeschFaculty of Biology, Microbiology, Ludwig-Maximilians-University of Munich, Martinsried, Germany.
Serena SchwenkertFaculty of Biology, Mass Spectrometry of Biomolecules Service Unit, Ludwig-Maximilians-Universität München, Martinsried, Germany.
Sebastián Riquelme-BarriosFaculty of Biology, Microbiology, Ludwig-Maximilians-University of Munich, Martinsried, Germany.
Sabine PeschekFaculty of Biology, Microbiology, Ludwig-Maximilians-University of Munich, Martinsried, Germany.
Max BergGoethe University Frankfurt, Faculty 14, Institute of Pharmaceutical Chemistry, Frankfurt, Germany.
Manh Dat HoangTUM School of Engineering and Design, Chair of Biochemical Engineering, Technical University of Munich, Garching, Germany.
Karin KleigreweBavarian Center for Biomolecular Mass Spectrometry (BayBioMS), TUM School of Life Sciences, Technical University of Munich, Freising, Germany.
Stefanie KaiserGoethe University Frankfurt, Faculty 14, Institute of Pharmaceutical Chemistry, Frankfurt, Germany.
Anna-Lena HeinsTUM School of Engineering and Design, Chair of Biochemical Engineering, Technical University of Munich, Garching, Germany.
Kirsten JungFaculty of Biology, Microbiology, Ludwig-Maximilians-University of Munich, Martinsried, Germany.ORCID 0000-0003-0779-6841

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acid resistance is an important trait of enterobacteria, enabling survival under extreme gastric acidity (pH < 2.5) and the moderately acidic conditions in the large intestine (pH 5-6). In

Indexed as

Escherichia coliEscherichia coli ProteinsFatty Acids, VolatileGlutamate DecarboxylaseGlutamic AcidRNA, TransferAntiportersGene Expression Regulation, BacterialHydrogen-Ion ConcentrationMembrane ProteinsAntiportersEscherichia coli ProteinsFatty Acids, VolatilegadA protein, E coligadB protein, E coliGlutamate DecarboxylaseGlutamic AcidMembrane ProteinsRNA, Transferacid resistanceglutamate decarboxylaseMnm pathwaytRNA modification

Identifiers

PMID42474318
PMCPMC13492128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.