Evidence map›Paper›PMID 42474311›Full record

ArticleJournal of bacteriology2026

AI-2 production in

Bibek G C, Shiqi Xu, Truman Tran, Chenggang Wu

Abstract read
In one paragraph

Article in Journal of bacteriology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bibek G CDepartment of Microbiology & Molecular Genetics, the University of Texas Health Science Center, Houston, Texas, USA.
Shiqi XuDepartment of Microbiology & Molecular Genetics, the University of Texas Health Science Center, Houston, Texas, USA.
Truman TranDepartment of Microbiology & Molecular Genetics, the University of Texas Health Science Center, Houston, Texas, USA.
Chenggang WuDepartment of Microbiology & Molecular Genetics, the University of Texas Health Science Center, Houston, Texas, USA.ORCID 0000-0002-5700-7188

Funding

Regulation in Fusobacterium-mediated coaggregationR01DE030895 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WU, CHENGGANG · 2021 to 2025
$1.7M
Study of essential genes in Fusobacterium nucleatumR21DE034542 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WU, CHENGGANG · 2024 to 2024
$429k
NIDCR NIH HHS R01 DE030895NIDCR NIH HHS R21 DE034542NIH HHS DE030895NIH HHS DE034542
6 · The paper itself

Abstract

Autoinducer-2 (AI-2) is a LuxS-dependent product of the activated methyl cycle (AMC) that functions as a quorum-sensing signal in diverse bacteria. IMPORTANCE: Periodontitis affects nearly half of adults in the United States and remains a leading cause of tooth loss worldwide.

Indexed as

Fusobacterium nucleatumHomoserineLactonesQuorum SensingBacterial ProteinsBiofilmsCarbon-Sulfur LyasesGene Expression Regulation, BacterialHumansVibrioVirulenceBacterial ProteinsCarbon-Sulfur LyasesHomoserineLactonesLuxS protein, BacteriaN-octanoylhomoserine lactoneactivated methyl cycleautoinducer 2Fusobacterium nucleatumluxS

Identifiers

PMID42474311
PMCPMC13492134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.