Evidence map›Paper›PMID 42474292›Full record

ArticleJournal of bacteriology2026

Anaerobic riboflavin degradation by human gut

Christian J Quiles Pérez, Alexandria Olzak, Aminata Fofana, Kamal Deep, Calissa Carlisle, Emily Bradley, Kathryn Kananen, Larry Beaver, Connor Skaggs, Justin A North and 1 more

Abstract read
In one paragraph

Article in Journal of bacteriology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Christian J Quiles PérezDepartment of Microbiology, The Ohio State University, Columbus, Ohio, USA.ORCID 0009-0001-6955-0890
Alexandria OlzakDepartment of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Aminata FofanaDepartment of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Kamal DeepDepartment of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Calissa CarlisleDepartment of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Emily BradleyDepartment of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Kathryn KananenDepartment of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Larry BeaverDepartment of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Connor SkaggsDepartment of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Justin A NorthDepartment of Microbiology, The Ohio State University, Columbus, Ohio, USA.ORCID 0000-0002-4210-5463
Patrick H BradleyDepartment of Microbiology, The Ohio State University, Columbus, Ohio, USA.ORCID 0000-0002-9231-8344

Funding

National Metabolomics Data Repository - nextgen Metabolomics WorkbenchU2CDK119886 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUBRAMANIAM, SHANKAR · 2018 to 2021
$12.7M
Biomedical Data Commons Workbench (BDCW)OT2OD030544 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUBRAMANIAM, SHANKAR · 2020 to 2024
$3.2M
Web Portal CoreU2CDK119889 · NIDDK · UNIVERSITY OF FLORIDA · PI CONLON, MICHAEL · 2018 to 2021
$1.9M
Interrogating function, regulation, and interactions in a clade of prevalent human gut microbesR35GM151155 · NIGMS · OHIO STATE UNIVERSITY · PI Patrick Joseph Bradley · 2023 to 2026
$1.5M
NIDDK NIH HHS U2C DK119886NIDDK NIH HHS U2C DK119889NIGMS NIH HHS R35 GM151155NIGMS NIH HHS R35GM151155NIH HHS OT2 OD030544The Ohio State University ERIK awardThe Ohio State University Startup funds
6 · The paper itself

Abstract

Vitamins mediate a web of cross-feeding interactions in the human gut. Many gram-positive gut microbes, in particular, are predicted to be vitamin auxotrophs. Previous studies of these microbes, however, have tended to use rich media, precluding controlled perturbations of low-abundance nutrients. We tested the ability of diverse

Indexed as

EubacterialesGastrointestinal MicrobiomeRiboflavinAnaerobiosisAnimalsCulture MediaFlavinsHumansMiceNucleotidyltransferasesPhosphotransferases (Alcohol Group Acceptor)7,8-dimethylalloxazineCulture MediaFlavinsFMN adenylyltransferaseNucleotidyltransferasesPhosphotransferases (Alcohol Group Acceptor)Riboflavinriboflavin kinaseanaerobic catabolic pathwayscellular redox statusgut microbiomehydroxyethylflavinLachnospiraceaelumichromemetabolismriboflavin

Identifiers

PMID42474292
PMCPMC13492142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.