Evidence map›Paper›PMID 42474259›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2026

Trichodermin exhibits potent anti-glioblastoma activity by inducing cell cycle arrest and apoptosis, suppressing invasion, and enhancing temozolomide efficacy.

Hung-Pei Tsai, Tzong-Huei Lee, Hong-Liang Lin, Tzu-Wei Lin, Wen-Hsin Chang, Chien-Ju Lin

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hung-Pei TsaiDivision of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Tzong-Huei LeeInstitute of Fisheries Science, National Taiwan University, Taipei, Taiwan.
Hong-Liang LinSchool of Pharmacy, College of Pharmacy, National Defense Medical University, Taipei, Taiwan.
Tzu-Wei LinSchool of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan.
Wen-Hsin ChangDepartment of Sports Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chien-Ju LinSchool of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trichodermin, a sesquiterpene antibiotic from

Indexed as

Antineoplastic AgentsApoptosisCell Cycle CheckpointsGlioblastomaTemozolomideTrichoderminAnimalsCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansMiceMolecular StructureNeoplasm InvasivenessStructure-Activity RelationshipTumor Cells, CulturedAntineoplastic AgentsTemozolomideTrichoderminapoptosisepithelial-mesenchymal transitionglioblastomatemozolomideTrichodermin

Identifiers

PMID42474259
PMCPMC13386590

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.