ArticleMicrobiology spectrum2026
Pathogenic spectrum, antibiotic resistance, and risk factors for 28-day mortality in pediatric bloodstream infection-associated sepsis: a 10-year retrospective cohort study.
Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Sepsis induced by a bloodstream infection (BSI) is a common cause of mortality in pediatric intensive care units. Currently, there is a lack of data for sepsis from southwest China. This study involved a 10-year retrospective analysis to summarize pathogen and drug resistance features of sepsis induced by BSI and analyze risk factors for 28-day mortality. A total of 311 pediatric patients with sepsis induced by a BSI were identified with the following characteristics: males, 60.8%; average age, 26 (5.6, 108.0) months; and 28-day mortality rate, 20.3%. The incidence of septic shock and acute kidney injury was 51.8% and 26.0%, respectively. Polymicrobial growth was demonstrated in 11 cultures. A total of 305 pathogens were isolated, as follows: 164 strains (53.8%) were gram-positive bacteria, 125 strains (41.0%) were gram-negative bacteria, and 16 strains (5.2%) were fungi. The most frequently isolated pathogens were
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