Evidence map›Paper›PMID 42474179›Full record

ArticleMicrobiology spectrum2026

Matteo Chiacchiaretta, Rita Sorrentino, Nadia Bresciani, Alessandra Aiello, Valentina Vanini, Samuel Zambrano, Davide Mazza, Federica Cugnata, Daniela Maria Cirillo, Alessandra Agresti and 2 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Matteo Chiacchiaretta *Emerging Bacterial Pathogens Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy.ORCID 0000-0003-3386-377X
Rita Sorrentino *Emerging Bacterial Pathogens Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy.ORCID 0000-0001-9674-0959
Nadia BrescianiEmerging Bacterial Pathogens Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy.
Alessandra AielloTranslational Research Unit, National Institute for Infectious Diseases-IRCCS L. Spallanzani, Rome, Italy.ORCID 0000-0003-2681-9383
Valentina VaniniTranslational Research Unit, National Institute for Infectious Diseases-IRCCS L. Spallanzani, Rome, Italy.ORCID 0000-0001-8476-964X
Samuel ZambranoVita-Salute San Raffaele University, Milan, Italy.ORCID 0000-0002-9384-2017
Davide MazzaVita-Salute San Raffaele University, Milan, Italy.ORCID 0000-0003-2776-4142
Federica CugnataUniversity Center for Statistics in the Biomedical Sciences (CUSSB), Vita-Salute San Raffaele University, Milan, Italy.ORCID 0000-0002-1886-569X
Daniela Maria CirilloEmerging Bacterial Pathogens Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy.ORCID 0000-0001-6415-1535
Alessandra AgrestiDivision of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0001-5006-9506
Delia GolettiTranslational Research Unit, National Institute for Infectious Diseases-IRCCS L. Spallanzani, Rome, Italy.ORCID 0000-0001-8360-4376
Paolo MiottoEmerging Bacterial Pathogens Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy.ORCID 0000-0003-4610-2427

Funding

Ministero della Salute GR-2016-02364014
6 · The paper itself

Abstract

Therapies counteracting pathogen-induced immune modulation of the host responses represent a promising improvement for tuberculosis treatments. Despite the documented role of host immune heterogeneity and bacterial genotypic background in determining infection outcomes, their interplay remains largely uncharacterized. We investigated the

Indexed as

MacrophagesMycobacterium tuberculosisPhagosomesTuberculosisHost-Directed TherapyHost-Pathogen InteractionsHumansHydrogen-Ion ConcentrationPhenotypeapoptosisautophagylive confocal microscopyphagosome acidificationsingle-cell

Identifiers

PMID42474179
PMCPMC13532232

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.