ArticleJournal of developmental origins of health and disease2026
Developmental origins of ADHD: sex-specific influences of early life unpredictability on symptom profiles.
Article in Journal of developmental origins of health and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Exposure to early life adversity (ELA) increases risk of poor mental health outcomes, including attention deficit/hyperactivity disorder (ADHD). In fact, ELA, especially in the form of "household ACEs" (e.g., socioeconomic disadvantage, incarceration of a caregiver), is among the most robust environmental predictors of a later ADHD diagnosis. Exposure to unpredictability is an understudied form of ELA that captures instability or inconsistency in routines, household experiences, and family relationships. The purpose of this study was to examine associations between unpredictability and ADHD symptoms in children and adolescents. Participants were drawn from two independent cohorts (Cohort 1:
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