Evidence map›Paper›PMID 42473593›Full record

ArticleIranian journal of biotechnology2026

Exploring the Dynamic Interplay of Carbon Nanotubes with Apoptosis

Shirin Lotfipanah, Leila Saremi, Yasaminsadat Rafieitabatabaei, Masoud Asgari, Zahra Hajebrahimi

Abstract read
In one paragraph

Article in Iranian journal of biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shirin LotfipanahDepartment of Biology, Shahid Beheshti Higher Education Center, Farhangian University, Tehran, Iran.
Leila SaremiDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Yasaminsadat RafieitabatabaeiEastern Mediterranean University, Department of Medicine, North Cyprus via Mersin 10, 99628, Turkey.
Masoud AsgariDepartment of Biology, Shahid Beheshti Higher Education Center, Farhangian University, Tehran, Iran.
Zahra HajebrahimiKhayyam Research Institute, Ministry of Science Research and Technology, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Carbon nanotubes (CNTs) are carbon-based nanomaterials. They have been widely used in environmental technologies and in biomedical fields. Objectives: This study examines the impact of carboxyl-functionalized multi-walled (MWCNTs) and single-walled carbon nanotubes (SWCNTs) on apoptosis in Jurkat cells and Wistar rats. Materials and Methods: The methods included functionalizing CNTs, conducting cell culture experiments with Jurkat cells, and performing Results: Results showed successful CNT functionalization and a slight reduction in cell viability in exposed groups. Gene expression analysis in Jurkat cells treated by MWCNTs and SWCNTs revealed significant upregulation of pro-apoptotic genes ( Conclusion: CNT exposure led to significant modulation of apoptotic pathways in Jurkat cells, including alterations in gene expression of some members of the

Indexed as

ApoptosisBcl-2 familyCancerCarbon nanotubesCytotoxicityIAP family

Identifiers

PMID42473593
PMCPMC13380539

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.