ArticleInternational medical case reports journal2026
Oral Histoplasmosis in an Immunocompetent Male Diagnosed by Culture, Histopathology, and MetaCAP.
Article in International medical case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Histoplasmosis is a systemic fungal infection caused by the dimorphic fungus Case Presentation: We report a case of oral granulomatous histoplasmosis in a 53-year-old immunocompetent male, initially suspected of having lymphoma or tuberculosis. To our knowledge, this is an exceptional case of oral histoplasmosis diagnosed in an immunocompetent patient through a combination of tissue fungal culture, pathological biopsy, and metagenomic capture sequencing (metaCAP). Conclusion: The case highlights the importance of considering fungal infections in persistent oral lesions of immunocompetent patients. It also demonstrates that metaCAP, alongside conventional culture and histopathology, can facilitate a definitive diagnosis in challenging cases.
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