Evidence map›Paper›PMID 42473557›Full record

ReviewInternational journal of nanomedicine2026

Biomaterials and Nanomedicine for Mucosal Repair and Inflammation Control in Interstitial Cystitis/Bladder Pain Syndrome: An Extensive Review.

Xiao Yang, Yu Pan, Wenjie Tian, Ranwei Li, Yinchun Wang, Min Wang, Zehua Yin, Yi Zhang

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiao YangDepartment of Urology, The Second Hospital of Jilin University, Changchun, 130021, People's Republic of China.
Yu PanDepartment of Urology, The Second Hospital of Jilin University, Changchun, 130021, People's Republic of China.
Wenjie TianDepartment of Urology, The Second Hospital of Jilin University, Changchun, 130021, People's Republic of China.
Ranwei LiDepartment of Urology, The Second Hospital of Jilin University, Changchun, 130021, People's Republic of China.
Yinchun WangDepartment of Urology, The Second Hospital of Jilin University, Changchun, 130021, People's Republic of China.ORCID 0009-0000-3517-3057
Min WangDepartment of Urology, The Second Hospital of Jilin University, Changchun, 130021, People's Republic of China.
Zehua YinDepartment of Urology, The Second Hospital of Jilin University, Changchun, 130021, People's Republic of China.
Yi ZhangDepartment of Urology, The Second Hospital of Jilin University, Changchun, 130021, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interstitial cystitis (IC), also known as bladder pain syndrome (BPS), is a chronic and devastating urologic disease. Its characteristics include the damage to the barrier function of bladder mucosa, inflammation related to nerve activity and chronic pelvic pain. Traditional treatments often only alleviate symptoms and cannot fundamentally treat this disease. This has inspired to seek new opportunities and strategies to use biomaterials and nanomedicine to reverse tissue damage and pain in patients with this disease. In this review, we comprehensively summarized the latest advances in innovative strategies for bladder mucosal repair and inflammation modulation. This includes glycosaminoglycan mimetics, nanomaterial-based drug delivery systems, stem cells and exosome-based nanomedicine, platelet-rich plasma, and other emerging nanomaterial-related therapeutic approaches. Moreover, we also explored their potential mechanisms of action, valuable results from preclinical and clinical studies, current challenges, and future possibilities for clinical applications. This review may promote the prospect of targeted multifunctional strategies to improve the clinical treatment of IC/BPS.

Indexed as

Biocompatible MaterialsCystitis, InterstitialNanomedicineAnimalsDrug Delivery SystemsHumansInflammationMucous MembraneUrinary BladderBiocompatible Materialsbiomaterialsbladder pain syndromeinflammation modulationinterstitial cystitismucosa regenerationnanomedicine

Identifiers

PMID42473557
PMCPMC13380952

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.