Evidence map›Paper›PMID 42473519›Full record

ArticleCureus2026

Aesthetic Chin Retrusion Enhancement With Non-animal Stabilized Hyaluronic Acid-High Density (NASHA-HD™) Filler.

Marcus H A Morais, Cássio Guimarães, Francine Papaiordanou, Stephanie Oliveira, Alessandra Nogueira, Rafael Tomaz Gomes

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marcus H A MoraisMedicine, Universidade Federal De Minas Gerais, Belo Horizonte, BRA.
Cássio GuimarãesDermatology, Clinical Practice, Belo Horizonte, BRA.
Francine PapaiordanouDermatology, Clinical Practice, Sao Paulo, BRA.
Stephanie OliveiraMedical Affairs, Galderma, Sao Paulo, BRA.
Alessandra NogueiraMedical Affairs, Galderma, Sao Paulo, BRA.
Rafael Tomaz GomesMedical Affairs, Galderma, Sao Paulo, BRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChin projection is a critical component of lower face aesthetics, influencing facial balance, youthfulness, and sexual dimorphism.

methodsThis retrospective case series provides short-term, real-world observations on the use of Non-animal Stabilized Hyaluronic Acid - High Density (NASHA-HD™) injectable for chin augmentation as part of a combined lower-face hyaluronic acid (HA) filler treatment approach. Each patient received 1 mL of High-Animal Stabilized Hyaluronic Acid (HASHA™) administered as supraperiosteal boluses in the chin, distributed according to the patient's needs. For a comprehensive facial approach, complementary injections of HA fillers based on Optimal Balance Technology (OBT

resultsResults demonstrated high patient satisfaction, natural aesthetic outcomes, a natural look on the chin, and a favorable safety profile with only mild and transient adverse events. Independent Global Aesthetic Improvement Scale (iGAIS)-physician assessment demonstrated global aesthetic improvement and enhanced facial proportionality in most patients. This holistic approach achieved satisfactory projection and contour enhancement using low product volumes.

conclusionsThis article underscores the importance of using high G' fillers for structural support, and flexible fillers for dynamic zones, particularly in the diverse population, which presents a wide range of facial morphologies requiring personalized aesthetic approaches.

Indexed as

ching primehyaluronic acid dermal fillerslower facenasha-hd™

Identifiers

PMID42473519
PMCPMC13380962

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.