Evidence map›Paper›PMID 42473118›Full record

ReviewAdvanced healthcare materials2026

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring.

Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio-da-Silva, Alireza Dolatshahi-Pirouz, Gorka Orive

Abstract readReview
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In one paragraph

Review in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maryam KamaeiNanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), Karaj, Iran.
Hesam MohammadiDepartment of Materials Engineering, Isfahan University of Technology, Isfahan, Iran.
Shamim GolafshanKnight Foundation School of Computing and Information Sciences, Florida International University, Miami, Florida, USA.
Mojtaba AlehosseiniDepartment of Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS), University of Genoa, Genova, Italy.
Mahsa MohammadzadehDepartment of Materials Engineering, Isfahan University of Technology, Isfahan, Iran.
Atefeh GolshiraziDepartment of Materials Engineering, Isfahan University of Technology, Isfahan, Iran.
Nasim GolafshanDepartment of Health Technology, Technical University of Denmark, Lyngby, Denmark.
Tatiane Eufrásio-da-SilvaDepartment of Health Technology, Technical University of Denmark, Lyngby, Denmark.
Alireza Dolatshahi-PirouzDepartment of Health Technology, Technical University of Denmark, Lyngby, Denmark.
Gorka OriveBasque Sustainable Pharmacy & Biotherapy Research Group, School of Pharmacy, University of the Basque Country (UPV/EHU), Vitoria-Gasteiz, Spain.ORCID https://orcid.org/0000-0002-0773-300X

Funding

Ministerio de Ciencia y Tecnología PID2022-139746OB-I00/AEI
6 · The paper itself

Abstract

Bone regeneration in orthopedics is a great challenge, as efficient recovery affects patient's quality of life. Common methods encounter different limitations regarding diagnosis, implantation, and bone health monitoring. Recent advances in artificial intelligence (AI), specifically machine learning (ML) algorithms, have presented opportunities to enhance these aspects by accurately analyzing imaging data. This provides detailed evaluations that help to determine bone condition and guide treatment strategies. ML models can facilitate a patient-specific approach to select and design intelligent implants by examining extensive biomaterial datasets to identify the best match for each patient's biomechanical and biological needs. Furthermore, ML models can analyze data to accurately predict bone-healing timelines, allowing clinicians to track recovery trends, and make timely interventions in potential complications. In clinical settings, ML tools assist with preoperative planning, postoperative follow-up, and the design of intelligent implants, offering more effective, data-driven decision-making and favorable outcomes in bone regeneration. Looking ahead, while ML advancements show promise for effective orthopedic therapies, challenges persist. ML could revolutionize bone regeneration in various ways and offer predictive insights that promote patient-centered orthopedic care. Altogether, considering the continued evolution of ML, its integration into clinical applications will be crucial for developing truly intelligent bone regeneration therapies.

Indexed as

Bone and BonesBone DiseasesMachine LearningOrthopedicsProstheses and ImplantsBone RegenerationHumansMonitoring, PhysiologicSoft Computingbone health monitoringintelligent diagnosisintelligent implantsmachine learningorthopedics

Identifiers

PMID42473118

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.