Evidence map›Paper›PMID 42472957›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Endoscopic surgical treatment of sinonasal Schneiderian papillomas: our experience.

Salvatore Poma, Andrea Comparetto, Domiziana Picone, Antonino Milia, Valerio Patti, Mauro Sergi, Cuffaro Luana, Domenico Michele Modica, Alberto Fucarino, Alessandro Pitruzzella

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Salvatore Poma *Department of Otorhinolaryngology, Villa Sofia-Cervello Hospital, Palermo, 90146, Italy.
Andrea Comparetto *Department of Otorhinolaryngology, Villa Sofia-Cervello Hospital, Palermo, 90146, Italy.
Domiziana PiconeDepartment of Biomedicine, Neurosciences and Advanced Diagnostics (BiND), University of Palermo, Palermo, 90127, Italy.
Antonino MiliaDepartment of Otorhinolaryngology, Villa Sofia-Cervello Hospital, Palermo, 90146, Italy.
Valerio PattiDepartment of Otorhinolaryngology, Villa Sofia-Cervello Hospital, Palermo, 90146, Italy.
Mauro SergiGeneral surgeon, freelance, Palermo, 90146, Italy.
Cuffaro LuanaDepartment of Otorhinolaryngology, Villa Sofia-Cervello Hospital, Palermo, 90146, Italy.
Domenico Michele ModicaDepartment of Otorhinolaryngology, Villa Sofia-Cervello Hospital, Palermo, 90146, Italy. domenicomichelemodica@gmail.com.ORCID http://orcid.org/0000-0003-2016-4101
Alberto Fucarino *Department of Theoretical and Applied Sciences, eCampus University, Novedrate, 22060, Italy.
Alessandro Pitruzzella *Department of Biomedicine, Neurosciences and Advanced Diagnostics (BiND), University of Palermo, Palermo, 90127, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSinonasal Schneiderian papillomas are uncommon epithelial tumors. Although benign, they may behave aggressively, recur after incomplete resection, and, particularly in the inverted subtype, be associated with carcinoma. Endoscopic surgery is now widely used when the site of attachment can be adequately exposed and treated.

objectiveTo review recurrence, morbidity, attachment-site documentation, and metachronous carcinoma in a single-surgeon endoscopic series of sinonasal Schneiderian papillomas treated with an attachment-site-oriented technique.

methodsWe retrospectively reviewed 71 patients with histologically confirmed Schneiderian papilloma treated exclusively by endoscopic surgery between January 2017 and December 2023. Preoperative work-up included nasal endoscopy, CT, and MRI. Disease extent was classified according to the Krouse system. Surgery was planned according to tumor extension and the suspected attachment site. Follow-up was based on serial endoscopic examinations; annual MRI was advised for long-term surveillance. Median follow-up was 46 months.

resultsKrouse staging identified 3 T1, 24 T2, 40 T3, and 4 T4 lesions. Histology included 58 inverted, 8 exophytic, and 5 oncocytic papillomas. Recurrence occurred in 3 patients (4.2%), all with inverted papilloma and advanced-stage disease (T3-T4). Complications were observed in 4 patients (5.6%), including three arterial bleeding episodes and one cerebrospinal fluid leak. One patient developed metachronous squamous cell carcinoma during follow-up.

conclusionIn this single-surgeon series, attachment-site-oriented endoscopic surgery was followed by few recurrences and acceptable morbidity during the available follow-up. Recurrences were observed only in advanced-stage inverted papillomas. These findings support careful treatment of the attachment site and long-term surveillance, while remaining limited by the retrospective design and heterogeneous follow-up.

Indexed as

EndoscopyNasal MucosaNose NeoplasmsPapillomaPapilloma, InvertedParanasal Sinus NeoplasmsAdultAgedAged, 80 and overFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingEndoscopic sinus surgeryInverted papillomaMetachronous carcinomaRecurrenceSchneiderian papillomaSinonasal tumors

Identifiers

PMID42472957
PMCPMC13615142

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