Evidence map›Paper›PMID 42472935›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Cone beam CT in the evaluation of paranasal sinuses in pediatric cystic fibrosis: radiological findings and dosimetric comparison with conventional maxillofacial CT in children with sinus pathology.

Maria Cristina Firetto, Mauro Campoleoni, Alessandro Barantani, Maurizio Cè, Maurizio Di Cicco, Renato Fabrizio, Laura Mascitti, Michaela Cellina, Gianpaolo Carrafiello

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maria Cristina FirettoRadiology Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 28, Milano, Italy.
Mauro CampoleoniMedical Physics Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 28, Milano, Italy.
Alessandro BarantaniMedical Physics Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 28, Milano, Italy.
Maurizio CèRadiology Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 28, Milano, Italy.
Maurizio Di CiccoENT Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 28, Milano, Italy.
Renato FabrizioPostgraduate School in Radiodiagnostics, Università Degli Studi Di Milano, Via Festa del Perdono 7, Milano, Italy.
Laura MascittiPostgraduate School in Radiodiagnostics, Università Degli Studi Di Milano, Via Festa del Perdono 7, Milano, Italy.
Michaela CellinaRadiology Department, ASST FBF SACCO, Ospedale Fatebenefratelli, Piazza Principessa Clotilde 3, 20121, Milano, Italy. michaela.cellina@asst-fbf-sacco.it.ORCID http://orcid.org/0000-0002-7401-1971
Gianpaolo CarrafielloRadiology Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 28, Milano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to compare the radiation dose to critical organs delivered by cone beam computed tomography (CBCT) versus conventional CT in the evaluation of sinonasal disease in pediatric patients with cystic fibrosis (CF).

methodsA retrospective study was conducted on 321 patients. The CF group included 155 patients (mean age 12.0 years) who underwent CBCT between 2016 and 2024. The control group consisted of 166 age-matched patients (mean age 14.4 years) who underwent CT for ENT indications. Organ doses (salivary glands, oral mucosa, and brain) were calculated using Monte Carlo-based software and compared using unpaired t-tests.

resultsCBCT resulted in significantly lower radiation doses across all evaluated organs. Mean dose to the salivary glands was 2.60 ± 0.72 mGy for CBCT versus 4.69 ± 3.02 mGy for CT (p < 0.01); oral mucosa received 2.88 ± 0.79 mGy (CBCT) vs. 4.04 ± 2.43 mGy (CT, p < 0.01); and brain dose was 1.31 ± 0.36 mGy (CBCT) vs. 5.51 ± 1.67 mGy (CT, p < 0.01).

conclusionCBCT provides a reliable and significantly safer alternative to CT for assessing paranasal sinus disease in pediatric CF patients. ADVANCES IN KNOWLEDGE: With substantially lower radiation exposure and excellent spatial resolution for bony structures, CBCT should be considered as the routine imaging method for longitudinal follow-up and preoperative evaluation in this vulnerable population.

Indexed as

Cone-Beam Computed TomographyCystic FibrosisParanasal Sinus DiseasesParanasal SinusesRadiation DosageTomography, X-Ray ComputedAdolescentChildChild, PreschoolFemaleHumansMaleRetrospective StudiesSalivary GlandsCone beam CTCTCystic fibrosisDosimetryPediatric

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.