Evidence map›Paper›PMID 42472929›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

The delayed mouth-opening technique: a staged inset strategy to prevent distal necrosis in perioral free flap reconstruction.

Weidong Zhang, Shijie Song, Kai Guo, Xiang He, Chenyang Tian, Dahai Hu, Yunchuan Wang

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Weidong Zhang *Department of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an, Shaanxi, 710032, China.
Shijie Song *Department of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an, Shaanxi, 710032, China.
Kai GuoDepartment of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an, Shaanxi, 710032, China.
Xiang HeDepartment of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an, Shaanxi, 710032, China.
Chenyang TianDepartment of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an, Shaanxi, 710032, China.
Dahai HuDepartment of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an, Shaanxi, 710032, China.
Yunchuan WangDepartment of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an, Shaanxi, 710032, China. wangyunchuan@fmmu.edu.cn.ORCID http://orcid.org/0009-0009-6364-4333

Funding

National Natural Science Foundation of China 82172210Xijing Hospital Advancement Program XJZT24CY38
6 · The paper itself

Abstract

purposeSevere perioral scarring from thermal injuries causes profound functional deficits. Circumferential free flap reconstruction risks distal ischemia upon acute oral aperture creation. This study evaluates a novel staged inset protocol using pre-expanded internal mammary artery perforator (IMAP) flaps to mitigate distal necrosis risk.

methodsA retrospective case series reviewed 12 patients with severe perioral scar contractures who underwent tissue expansion (Stage 1), scar excision and flap transfer with temporary 1- to 2-cm microstoma creation (Stage 2), and delayed definitive commissure division after 2 to 4 weeks (Stage 3). Outcomes included interincisal distance, dietary status, oral competence, patient satisfaction (Visual Analog Scale, VAS), and scar quality (Vancouver Scar Scale, VSS).

resultsAll primary facial flaps survived, with no distal necrosis. One primary facial flap required early re-exploration for venous thrombosis but was successfully salvaged. The mean interincisal distance improved from 15 mm preoperatively to 40 mm at a mean follow-up of 11.8 months. Preoperative drooling (n = 3) and dietary restrictions to liquids/semi-liquids (n = 3) were completely resolved. The mean VAS score was 8.3 ± 0.8, and VSS scores ranged from 2 to 4.

conclusionThe delayed mouth-opening protocol achieved complete flap survival, objective functional restoration, and favorable aesthetic outcomes, offering a highly reliable strategy to prevent distal necrosis in severe perioral reconstruction.

Indexed as

Free Tissue FlapsMouthPlastic Surgery ProceduresPostoperative ComplicationsTissue ExpansionAdultBurnsCicatrixContractureFemaleFollow-Up StudiesHumansMaleMiddle AgedNecrosisPatient SatisfactionDelayed mouth openingInternal mammary artery perforator flapMicrosurgeryPerioral reconstructionScar contracture

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.