Evidence map›Paper›PMID 42472918›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Sensorineural hearing loss in early childhood after passing newborn hearing screening.

I E C Smetsers, N Uilenburg, R J E Pennings, C P Lanting, F L J Cals

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

I E C SmetsersDepartment of Otorhinolaryngology and Head and Neck Surgery, Radboudumc, Geert Grooteplein Zuid 10, Nijmegen, The Netherlands. iris.smetsers@radboudumc.nl.ORCID http://orcid.org/0009-0000-2381-6430
N UilenburgDutch Foundation for the Deaf and Hard of Hearing Child, Amsterdam, Netherlands.
R J E PenningsDepartment of Otorhinolaryngology and Head and Neck Surgery, Radboudumc, Geert Grooteplein Zuid 10, Nijmegen, The Netherlands.
C P LantingDepartment of Otorhinolaryngology and Head and Neck Surgery, Radboudumc, Geert Grooteplein Zuid 10, Nijmegen, The Netherlands.
F L J CalsDepartment of Otorhinolaryngology and Head and Neck Surgery, Radboudumc, Geert Grooteplein Zuid 10, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe newborn hearing screening (NHS) program in the Netherlands consist of two rounds of otoacoustic emissions (OAE) and a third round of automated auditory brainstem responses (AABR). The program identifies about 200 newborns with sensorineural hearing loss (SNHL) annually, enabling early intervention. Nevertheless, a subgroup of patients passes the NHS but present with SNHL in early childhood. PURPOSE: To determine the number of patients diagnosed with SNHL (< 5 years) who initially passed their NHS, and characterize this group in terms of patient demographics, NHS results, hearing loss (HL) characteristics and etiology of, to identify opportunities for earlier detection.

methodsA retrospective descriptive study was conducted on patients (< 5 years) seen between 2014 and 2024, passed their NHS and had SNHL with an unknown cause, for which they underwent etiological diagnostics.

results119 patients with 205 ears were included. Three-fourth of patients had an abnormal speech and language development (SLD). A relatively large number of ears passed in the third AABR round (36%). HL characteristics were highly variable. An etiological diagnosis was found in 74 patients (62%), most commonly a genetic cause (40%) or a cochleovestibular malformation (18%).

conclusionsWe estimate that in the Netherlands approximately 50 patients per year present with SNHL (< 5 years) after passing their NHS, of which the majority manifest abnormal SLD. Highly variable HL characteristics and etiology make it difficult to identify them. Nevertheless, a possibility for earlier detection is a second screening for specific subgroups. No evidence of false negatives during NHS was found.

Indexed as

Hearing Loss, SensorineuralNeonatal ScreeningChild, PreschoolEarly DiagnosisEvoked Potentials, Auditory, Brain StemFemaleHearing TestsHumansInfantInfant, NewbornMaleNetherlandsOtoacoustic Emissions, SpontaneousRetrospective StudiesAutomated auditory brainstem responseNewborn hearing screeningOtoacoustic emissionsPass screeningSensorineural hearing loss

Identifiers

PMID42472918
PMCPMC13615143

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