ArticleAnnals of surgical oncology2026
Preoperative Radiologic Assessment of the Axilla in Locally Advanced Breast Cancer After Neoadjuvant Systemic Therapy: A Contemporary Comparison.
Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrior studies comparing different imaging modalities in assessing axillary response after neoadjuvant systemic therapy (NST) in locally advanced breast cancer (LABC) are limited. This study evaluated the efficacy of different imaging modalities in identifying residual lymphadenopathy after NST in modern cohort of LABC patients.
methodsA retrospective review was performed examining LABC patients undergoing NST followed by surgical axillary staging from 2018 to 2023. Patients with LABC (T3-4,N1-3 or any T stage with N2-3 disease) were included. Inflammatory breast cancer was excluded. The efficacy of US, MRI, and PET/CT in evaluating residual nodal disease and the variables associated with radiologic-pathologic concordance were analyzed.
resultsA total of 101 patients meeting inclusion were identified. Post-NST imaging included US (n = 57), MRI (n = 53), and PET/CT (n = 45). Ultrasound had the highest sensitivity of 71% and positive predictive value of 76%. PET/CT had the highest specificity of 73% and negative predictive value of 70%. MRI had the lowest performance in all diagnostic measures. There was a significant relationship between complete imaging response (CIR)-pathologic complete response (pCR) concordance and pretreatment nodal status (χ
conclusionsPost-NST imaging provides valuable information on treatment response in LABC. However, CIR should not preclude surgical axillary evaluation. Further studies investigating the relationships between pre-treatment nodal status in LABC patients and radiologic-pathologic complete response after NST are warranted.
Indexed as
Identifiers
42472753What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.