Evidence map›Paper›PMID 42472710›Full record

ReviewEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Sexual dysfunction after cauda equina syndrome: a systematic review of long-term outcomes.

Elie Najjar, Charles Trumble, Weronika Nocun, Rodrigo Muscogliati, Negin Nematiniaye Masooleh, Aymen Dar, Emily Lindridge, Khalid Salem, Nasir Quraishi, Michael Grevitt

Abstract readReview
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In one paragraph

Review in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elie NajjarCentre for Spinal Studies and Surgery, Queen´s Medical Centre, Nottingham, UK. elie.njjr@gmail.com.
Charles TrumbleCentre for Spinal Studies and Surgery, Queen´s Medical Centre, Nottingham, UK. Charles.trumble03@gmail.com.
Weronika NocunCentre for Spinal Studies and Surgery, Queen´s Medical Centre, Nottingham, UK. weronika.nocun@gmail.com.
Rodrigo MuscogliatiCentre for Spinal Studies and Surgery, Queen´s Medical Centre, Nottingham, UK. frankenspinesresearch@gmail.com.
Negin Nematiniaye MasoolehCentre for Spinal Studies and Surgery, Queen´s Medical Centre, Nottingham, UK.
Aymen DarMedical School, University of Nottingham, Nottingham, UK.
Emily LindridgeMedical School, University of Nottingham, Nottingham, UK.
Khalid SalemCentre for Spinal Studies and Surgery, Queen´s Medical Centre, Nottingham, UK.
Nasir QuraishiCentre for Spinal Studies and Surgery, Queen´s Medical Centre, Nottingham, UK.
Michael GrevittCentre for Spinal Studies and Surgery, Queen´s Medical Centre, Nottingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSexual dysfunction is a recognised but underreported outcome following cauda equina syndrome (CES), with existing evidence fragmented and methodologically heterogeneous. Its true prevalence and clinical significance remain unclear. To systematically evaluate the prevalence, characteristics, and predictors of long-term sexual dysfunction following CES.

methodsA systematic review was conducted in accordance with PRISMA guidelines. Studies reporting sexual function outcomes following CES were identified from database inception to 16 December 2025. Eligible studies included adult patients undergoing surgical decompression for CES with extractable long-term sexual function data. Data were synthesised narratively with exploratory quantitative pooling where appropriate.

resultsFive studies were included. Sexual dysfunction was common, with reported prevalence ranging from 48% to 67% and a pooled estimate of 58.4% at long-term follow-up. Dysfunction affected both men and women and extended beyond erectile dysfunction to include impairments in arousal, orgasm, and satisfaction. Studies using validated patient-reported outcome measures generally reported broader and higher burdens of dysfunction than studies relying on descriptive or neurological assessment alone. Limited evidence suggested associations with increasing age, longer duration of pre-operative bladder dysfunction, and markers of sacral nerve root involvement, including bowel dysfunction and perianal sensory loss. Timing of surgery was not consistently associated with long-term sexual outcomes. Baseline sexual function was rarely reported.

conclusionsSexual dysfunction affects more than half of patients following CES and represents a persistent and under-recognised component of long-term morbidity. Current evidence is limited by heterogeneity and lack of baseline assessment, but suggests that outcomes are driven more by severity of neural compromise than timing alone. Routine assessment using validated patient-reported measures should be incorporated into CES follow-up to better define recovery and guide patient counselling.

Indexed as

CESLong-term outcomesSexual dysfunctionSexual function

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.