Evidence map›Paper›PMID 42472483›Full record

ArticleThe Plant journal : for cell and molecular biology2026

Triple florigenic signaling in rice promotes stem elongation via transcriptional de-repression.

Giulio Vicentini, Greta Bertagnon, Fabio Dobetti, Francesca Giaume, Francesca Cazzaniga, Alessio Baldini, Giulia Ave Bono, Jan Maika, Selina Sterup Moore, Alessandro Bignardi and 6 more

Abstract read
In one paragraph

Article in The Plant journal : for cell and molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Giulio VicentiniDepartment of Agricultural and Environmental Sciences, University of Milan, Via Celoria 2, 20133, Milan, Italy.
Greta BertagnonDepartment of Agricultural and Environmental Sciences, University of Milan, Via Celoria 2, 20133, Milan, Italy.
Fabio DobettiDepartment of Agricultural and Environmental Sciences, University of Milan, Via Celoria 2, 20133, Milan, Italy.
Francesca GiaumeDepartment of Agricultural and Environmental Sciences, University of Milan, Via Celoria 2, 20133, Milan, Italy.
Francesca CazzanigaDepartment of Biosciences, University of Milan, Via Celoria 26, 20133, Milan, Italy.
Alessio BaldiniDepartment of Biosciences, University of Milan, Via Celoria 26, 20133, Milan, Italy.
Giulia Ave BonoDepartment of Biosciences, University of Milan, Via Celoria 26, 20133, Milan, Italy.
Jan MaikaInstitute for Developmental Genetics, Heinrich Heine University, Düsseldorf, North Rhine Westphalia, Germany.
Selina Sterup MooreDepartment of Biosciences, University of Milan, Via Celoria 26, 20133, Milan, Italy.
Alessandro BignardiDepartment of Agricultural and Environmental Sciences, University of Milan, Via Celoria 2, 20133, Milan, Italy.
Rüdiger SimonInstitute for Developmental Genetics, Heinrich Heine University, Düsseldorf, North Rhine Westphalia, Germany.ORCID https://orcid.org/0000-0002-1317-7716
Giorgio PerrellaDepartment of Biosciences, University of Milan, Via Celoria 26, 20133, Milan, Italy.ORCID https://orcid.org/0000-0001-8972-1733
Keisuke NagaiBioscience and Biotechnology Center of Nagoya University, Furo-Cho, Chikusa, Nagoya, Aichi, 464-8602, Japan.
Motoyuki AshikariBioscience and Biotechnology Center of Nagoya University, Furo-Cho, Chikusa, Nagoya, Aichi, 464-8602, Japan.
Fabio FornaraDepartment of Biosciences, University of Milan, Via Celoria 26, 20133, Milan, Italy.ORCID https://orcid.org/0000-0002-1050-0477
Vittoria BrambillaDepartment of Agricultural and Environmental Sciences, University of Milan, Via Celoria 2, 20133, Milan, Italy.

Funding

Agenzia Spaziale Italiana Moonrice- accordo n.2024-9-HH.0Agritech Next-GenerationEU CN00000022Agritech Next-GenerationEU D.D. 1032 17/06/2022
6 · The paper itself

Abstract

The beginning of the reproductive phase of cereals is marked by inflorescence formation and stem elongation. In rice, florigenic proteins encoded by HEADING DATE 3a (Hd3a) and RICE FLOWERING LOCUS T 1 (RFT1) coordinate both developmental transitions by inducing expression of floral identity genes at the apical meristem and establishing stem competence to respond to gibberellins. Stem elongation is repressed during the vegetative phase by the activity of PREMATURE INTERNODE ELONGATION 1 (PINE1), and the florigens reduce its transcription, thus relieving growth repression. Here, we first resolve the relationships occurring between regulatory factors at the shoot apical meristem and underlying stem tissues in controlling reproductive phase transitions. We next show that the PINE1 protein forms higher order complexes with TOPLESS-related and HISTONE DEACETYLASE proteins and is required to repress a set of target genes by reducing histone acetylation levels and increasing chromatin accessibility. We propose that PINE1 controls chromatin accessibility through histone deacetylation, preventing stem growth, and that florigenic proteins act upstream of growth-promoting signals.

Indexed as

FlorigenOryzaPlant ProteinsPlant StemsSignal TransductionChromatinGene Expression Regulation, PlantHistonesMeristemChromatinFlorigenHistonesPlant Proteinschromatin remodellingfloral transitionflorigensricestem elongationtranscriptional reprogramming

Identifiers

PMID42472483
PMCPMC13381055

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.