Evidence map›Paper›PMID 42472418›Full record

ArticleAnnals of biomedical engineering2026

The Effect of High-Demand Loading Conditions on Polyethylene Stresses in Total Joint Replacement of the Lumbar Spine at L5-S1.

Steven A Rundell, Hannah Spece, Ronald V Yarbrough, Steven M Kurtz

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Article in Annals of biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Steven A RundellExplico, Inc., Detroit, MI, USA.
Hannah SpeceImplant Research Core, School of Biomedical Engineering, Science, and Health System, Drexel University, Philadelphia, PA, USA. hspece@drexel.edu.ORCID http://orcid.org/0000-0002-2114-0358
Ronald V Yarbrough3Spine, Inc., Chattanooga, TN, USA.
Steven M KurtzImplant Research Core, School of Biomedical Engineering, Science, and Health System, Drexel University, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn this study, we introduce a method for evaluating the effects of high-demand spinal loading on polyethylene stresses in a lumbar total joint replacement (LTJR).

methodsA previously validated finite element model of the lumbar spine was virtually implanted with an LTJR at L5-S1 and subjected to loading generally above the standard in vitro Mode I wear testing. Specifically, three elevated loading conditions were considered: (1) flexion with 50th and 95th percentile male body weights; (2) flexion in combination with axial rotation and lateral bending for 50th and 95th percentile male body weights; and (3) uniaxial torsion under a worst-case load as defined by ASTM F2423.

resultsIn all three loading scenarios, bearing contact occurred within the intended spherical articulations, consistent with Mode I in vitro wear testing. No component impingement outside the spherical bearing surfaces was observed. The resulting contact and von Mises stresses, as well as effective plastic strains, remained below those predicted for Mode IV impingement simulations.

conclusionThis study provides an approach for evaluating the upper biomechanical loading limits for an LTJR design at L5-S1, extending beyond the 50th percentile conditions typically used in standard in vitro testing.

Indexed as

Finite element analysisL5–S1LoadingLumbar total joint replacementPolyethylene

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.