Evidence map›Paper›PMID 42472391›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Lateral lumbar interbody fusion to address pseudarthrosis after prior posterior spinal instrumentation.

Julia Wimmer, Jonathan Slawitsky, Tom Folkerts, Anna-Maria Mielke, Sachiel Newbrun, Bruno Verna, Pedro Rocha Torres, Jiaqi Zhu, Jennifer Shue, Andrew A Sama and 4 more

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Julia WimmerDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, USA.
Jonathan SlawitskyDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, USA.
Tom FolkertsDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, USA.
Anna-Maria MielkeDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, USA.
Sachiel NewbrunDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, USA.
Bruno VernaDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, USA.
Pedro Rocha TorresDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, USA.
Jiaqi ZhuCenter for Biostatistics, Hospital for Special Surgery, New York, USA.
Jennifer ShueDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, USA.
Andrew A SamaDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, USA.
Federico P GirardiDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, USA.
Frank P CammisaDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, USA.
Alexander P HughesDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, USA.
Marco D BurkhardDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, USA. burkhardm@hss.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLumbar pseudarthrosis revision is challenging for both patients and surgeons, with no standard approach. This study aimed to evaluate radiographic fusion and index-level re-revision rates after revision using lateral lumbar interbody fusion (LLIF), comparing standalone LLIF (SA-LLIF) and circumferential LLIF with posterior revision (360°-LLIF). Secondary outcomes included perioperative parameters and sagittal alignment.

methodsThis retrospective, single-center cohort study included patients undergoing LLIF for lumbar pseudarthrosis between 2007 and 2023 with ≥ 1-year follow-up. Patients were stratified into SA-LLIF and 360°-LLIF groups. Fusion was assessed at one year using the Bridwell grading system (grades I-II considered fused). Perioperative parameters, re-revision, and sagittal alignment were evaluated.

resultsThirty-eight patients were included (SA-group: n = 26; 360°-group: n = 12). Groups were comparable except for a higher BMI in the 360°-group (p = 0.035). Overall fusion was 84.2%, with rates of 80.8% in SA-LLIF and 91.7% in 360°-LLIF (p = 0.392). No patient required re-revision for non-union; one 360° patient underwent wound revision. Operative time (233 vs. 84 min, p = 0.005), and estimated blood loss (625 vs. 100 mL, p = 0.001) were higher in the 360°-group. Length of stay and sagittal alignment parameters were similar between groups.

conclusionBoth 360°-LLIF and SA-LLIF may represent viable revision strategies for pseudarthrosis after posterior instrumentation, each with distinct advantages. Fusion rates were numerically higher with 360°-LLIF but not statistically different, and no patient in either group required secondary revision surgery for non-union. SA-LLIF was associated with shorter operative times and reduced EBL. Findings should be interpreted cautiously given the small sample size.

Indexed as

Circumferential fusionLateral lumbar interbody fusionLumbar pseudarthrosisRevision surgeryStandalone LLIF

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.