ArticleMolecular carcinogenesis2026
SFRP2
Article in Molecular carcinogenesis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolic reprogramming is a hallmark of cancer, enabling tumor cells to meet the demands of rapid growth and survival. Within tumor microenvironment (TME), cancer-associated fibroblasts (CAFs) influence tumor metabolism through metabolic crosstalk. However, role of CAF-derived factors in regulating glutamine metabolism in laryngeal squamous cell carcinoma (LSCC) remains unclear. Primary fibroblasts were isolated from LSCC tumors and adjacent tissues and classified as CAFs or normal fibroblasts (NFs). These were co‑cultured with LSCC cell lines to assess effects on proliferation, migration, invasion, stemness, and chemoresistance using assays such as CCK‑8, EdU, sphere formation, Transwell migration/invasion, and real‑time RTCA assays. Exosomes were harvested from fibroblast-conditioned media, characterized by TEM, NTA, and Western blotting, and used to treat LSCC cells. Metabolic profiling included Seahorse measurements, TCA metabolites, ATP content, glutamine uptake ([
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.