Evidence map›Paper›PMID 42471872›Full record

ReviewNigerian medical journal : journal of the Nigeria Medical Association

Evaluation and Impact of Pharmaceutical Residues from Hospital Waste in Lagos State on Dissolved Oxygen in Water.

Iretiolu C Lasore, Lajide L, Zacchaeus S Ololade, Joshua O Babayemi

Abstract readReview
In one paragraph

Review in Nigerian medical journal : journal of the Nigeria Medical Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Iretiolu C LasoreDepartment of Chemical Sciences, Anchor University, Lagos, Nigeria.
Lajide LDepartment of Chemistry, Medicinal and Organic Chemistry Unit, University of Medical Sciences, Ondo, Nigeria.
Zacchaeus S OloladeDepartment of Pharmaceutical and Medicinal Chemistry, University of Medical Sciences, Ondo, Nigeria.
Joshua O BabayemiDepartment of Biosciences and Biotechnology, University of Medical Sciences, Ondo, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study assessed the influence of pharmaceutical residues from hospital waste on dissolved oxygen (DO) levels in water sources near four hospitals in Lagos State, Nigeria. Methodology: A total of 35 water samples were collected from boreholes, wells, and taps adjacent to hospital waste sites and analyzed for ciprofloxacin, paracetamol, and bromazepam residues using high-performance liquid chromatography (HPLC), alongside DO measurements with a calibrated digital meter. Results: Residue concentrations varied across sites, with paracetamol levels exceeding WHO guidelines in several samples, potentially contributing to the observed low DO (<2 mg/L) across all locations-well below thresholds for aquatic life (5-6 mg/L) and drinking water (>6.5 mg/L). Hospital location D exhibited the highest residue levels, followed by location B, while locations A, C, and the control (E) showed lower concentrations. Statistical analyses (t-tests) indicated no significant differences for ciprofloxacin and bromazepam relative to permissible limits (p > 0.05), but paracetamol was significantly elevated (p < 0.05). Conclusion: These findings highlight an association between pharmaceutical residues and DO depletion, underscoring risks to aquatic ecosystems and human health. Recommendations include enhanced hospital waste segregation, advanced water treatment protocols, and policy reforms to enforce pharmaceutical disposal standards, aligning with SDGs 3, 6, and 11 for sustainable health and water management.

Indexed as

Dissolved oxygenHospital wasteImpactPharmaceutical residuesWater

Identifiers

PMID42471872
PMCPMC13379849

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.