ArticleHealth and quality of life outcomes2026
Empowerment and quality of life through cancer prevention in people experiencing homelessness: evaluating the Health Navigator Model.
Article in Health and quality of life outcomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05406687 (Cancer Prevention and Early Detection Among the Homeless Population in Europe), which is not on this map. Not yet cited in PubMed.
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The trial behind it
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Cancer Prevention and Early Detection Among the Homeless Population in Europe: Co-adapting and Implementing the Health Navigator Model
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16 authors.
Funding
Abstract
backgroundPeople experiencing homelessness (PEH) face significant barriers to accessing cancer prevention services. The CANCERLESS project co-developed and implemented the Health Navigator Model (HNM) - a person-centred approach using trained health navigators to provide tailored support, promote cancer awareness, and facilitate access to preventive services - in Austria, Greece, Spain, and the UK. This study examined the HNM's impact on healthcare empowerment, health-related quality of life (HRQoL), and self-rated health among PEH.
methodsThis non-randomised, single-arm study included 652 PEH from 16 pilot sites in four European countries between June 2022 and December 2023. Healthcare empowerment, HRQoL, and self-rated health were assessed using the healthcare empowerment questionnaire and the EQ-5D-5L (including the EQ Visual Analogue Scale) when participants entered and completed the intervention. A per-protocol analysis with repeated measures ANOVA revealed changes over time and between countries.
resultsParticipants were predominantly male (64.1%) and middle-aged (mean 47.4, SD 13.8), with secondary education (58.0%), and varied legal status and experiences of homelessness. Despite a drop-out rate of 57.5%, significant improvements in overall healthcare empowerment (F = 44.325, p<.001, η²=0.026), HRQoL (F = 4.421, p = .036, η²=0.002), and self-rated health (F = 16.945, p<.001, η²=0.011) were observed, particularly in Austria and the UK.
conclusionsThe HNM holds promise for improving healthcare empowerment and HRQoL among PEH, but context-specific factors and a considerable drop-out pose challenges.
trial registrationThis study was registered retrospectively on June 6, 2022, in the registry of ClinicalTrials.gov under the number NCT05406687.
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