ArticleBMC surgery2026
Evaluation of pancreatic stump binding and ligation in reducing postoperative pancreatic fistula after distal pancreatectomy: a retrospective cohort study.
Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThis study evaluates the efficacy of pancreatic stump binding and ligation (PSBL) in reducing postoperative pancreatic fistula (POPF) after distal pancreatectomy (DP).
methodsA retrospective cohort analysis included 217 patients undergoing DP between 2015 and 2022. Patients were classified into two groups: those receiving PSBL (B-Group, n = 96) and those without (NB-Group, n = 121). The primary outcome was incidence of clinically relevant POPF (Grade B/C).
resultsThe B-Group demonstrated lower POPF rates (11.5% vs. 28.9%, P = 0.003) compared to the NB-Group, with grade B fistulas particularly reduced (P = 0.002). Multivariate analysis identified independent risk factors for POPF: BMI ≥ 28 kg/m
conclusionsIn this retrospective cohort, PSBL is a promising, feasible technique associated with reduced clinically relevant POPF incidence after DP. Given the retrospective design, these findings are hypothesis-generating and warrant prospective, multicenter validation.
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