Evidence map›Paper›PMID 42471562›Full record

ArticleBMC infectious diseases2026

Pattern of bacterial uropathogens and multidrug resistance in selected private laboratories, Ibb city, Yemen: a retrospective study.

Najm Aldeen Mohammed, AbdulraKeeb Shomais, Ramez Alshameri, Mohammed Alnawah, Hamed Al-Shoaibi, Haroon Al-Qaisi, Abdulrahman Soltan, Ahmed Al-Mashraqi, Amjad Al Falaei, Wadhah Hassan Edrees and 2 more

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Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Najm Aldeen MohammedDepartment of Urology Surgery, Faculty of Medicine and Health Sciences, Ibb University, Ibb, Yemen.
AbdulraKeeb ShomaisScientific Research Unit, Faculty of Medicine and Health Sciences, Ibb University, Ibb, Yemen.ORCID http://orcid.org/0009-0003-4304-6615
Ramez AlshameriFaculty of Medicine and Health Sciences, Ibb University, Ibb, Yemen.
Mohammed AlnawahFaculty of Medicine and Health Sciences, Ibb University, Ibb, Yemen.
Hamed Al-ShoaibiFaculty of Medicine and Health Sciences, Ibb University, Ibb, Yemen.
Haroon Al-QaisiFaculty of Medicine and Health Sciences, Ibb University, Ibb, Yemen.
Abdulrahman SoltanFaculty of Medicine and Health Sciences, Ibb University, Ibb, Yemen.
Ahmed Al-MashraqiFaculty of Medicine and Health Sciences, Ibb University, Ibb, Yemen.
Amjad Al FalaeiFaculty of Medicine and Health Sciences, Ibb University, Ibb, Yemen.
Wadhah Hassan EdreesMedical Microbiology Department, Faculty of Medicine and Health Sciences, Hajjah University, Hajjah, Yemen.ORCID http://orcid.org/0000-0002-7799-0466
Wadee Abdullah Al-ShehariMedical Microbiology Department, Faculty of Medicine and Health Sciences, Ibb University, Ibb, Yemen. dr.wadee40@yahoo.com.ORCID http://orcid.org/0000-0002-3375-0559
Abdulrahman AlhemiarFaculty of Medicine and Health Sciences, Ibb University, Ibb, Yemen.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUrinary tract infections (UTIs) represent a significant global health burden, and rising antimicrobial resistance (AMR) threatens effective empirical treatment. Ibb City lacks contemporary, comprehensive resistance data from large cohorts that are essential to guide treatment decisions and antimicrobial stewardship. This analysis aimed to determine the spectrum of bacterial uropathogens and evaluate the prevalence of multidrug resistance (MDR).

methodsA retrospective analysis was conducted on 905 non-duplicate, consecutive culture-confirmed UTI cases in Ibb between August 2024 and August 2025. Antimicrobial susceptibility testing was performed for 42 antibiotics across multiple classes using the Kirby-Bauer disk diffusion method. Statistical analyses included descriptive statistics, chi-square tests, Fisher's exact test, Cochran-Armitage trend test, and Monte Carlo simulation for contingency tables with low expected cell counts.

resultsThe majority of cases were recorded among females with 593 cases (65.5%) and young adults aged 19-35 years with 462 cases (51.0%). Escherichia coli was the most frequently isolated pathogen (387, 42.8%), followed by Staphylococcus saprophyticus (300, 33.1%), Staphylococcus aureus (131, 14.5%), Klebsiella spp. (30, 3.3%), Pseudomonas aeruginosa (21, 2.3%), Enterobacter spp. (21, 2.3%), Proteus spp. (12, 1.3%), and Acinetobacter spp. (3, 0.3%). The significant associations were observed between uropathogen distribution and demographic factors, including sex and age group (P < 0.001). The overall MDR prevalence was 27.8% (252/905). MDR prevalence showed a significant positive correlation with age (P < 0.001), increasing progressively from 12.7% in pediatric patients to 38.6% in elderly patients. Enterobacter spp. had the highest MDR rate (42.9%), followed by Proteus spp. (41.7%), E. coli (35.4%), P. aeruginosa (33.3%), S. aureus (19.8%), and S. saprophyticus (19.3%).

conclusionThe finding revealed an increased burden of antimicrobial resistance in the study area, with an association between rising rates of MDR and advancing age. This necessitates a review of antimicrobial use protocols and the implementation of effective strategies to monitor the spread of antibiotic-resistant strains. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Anti-Bacterial AgentsBacteriaDrug Resistance, Multiple, BacterialUrinary Tract InfectionsAdolescentAdultAgedChildChild, PreschoolFemaleHumansInfantMaleMicrobial Sensitivity TestsMiddle AgedPrevalenceAnti-Bacterial AgentsAntimicrobial stewardshipAntimicrobial susceptibilityExtended-spectrum beta-lactamaseMultidrug resistanceUrinary tract infectionYemen

Identifiers

PMID42471562
PMCPMC13670484

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.