ReviewAnnals of biomedical engineering2026
Emerging Technologies for Assisted Fracture Reduction: A Systematic Review.
Review in Annals of biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBone fractures pose a major healthcare challenge, affecting millions of people worldwide. Achieving excellent fracture reduction is critical for successful outcomes yet remains difficult with current surgical tools. Poor reduction quality contributes significantly to implant failure and reoperation rates. Consequently, various technology-assisted solutions such as 3D printing, robotics, and computer-assisted systems have been proposed to support surgeons in achieving optimal reduction. This article presents a systematic review of these emerging technologies designed to support fracture reduction.
methodsA systematic search of PubMed, Web of Science, and Scopus was conducted on October 31, 2025, covering studies published between January 2016 and October 2025. Inclusion criteria focused on new technologies applied pre- or intraoperatively to assist fracture reduction. After screening and applying exclusion criteria, 62 studies were included and categorized into three domains: 3D printing (including anatomical models, surgical guides/tools, and implants), Robot-Assisted Fracture Reduction (RAFR), and computer-assisted technologies. Reported outcomes included operative time, blood loss, radiation exposure, reduction quality, and functional recovery.
results3D printing was the most frequently studied, primarily through anatomical models, mirror models, and patient-specific surgical guides. Across studies, 3D printing consistently reduced operative time (16-50%) and blood loss (15-75%) compared with conventional methods, though limited by long production times and regulatory constraints. RAFR systems, particularly navigation-focused platforms, demonstrated reduced radiation exposure (20-60%) and improved surgical precision. Computer-assisted approaches are emerging but with limited clinical validation to date.
conclusionsTechnology-assisted solutions can provide measurable benefits in the reduction of fractures. Among the reviewed technologies, navigation-based RAFR systems and 3D-printed surgical guides appear to have relatively stronger clinical support, though evidence remains limited. However, significant barriers remain, including workflow integration, cost, and regulatory approval. Future research should focus on accelerating translation from prototype to practice, with emphasis on clinical validation and real-time usability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.