ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2026
Expert consensus recommendations for the management of biochemical recurrence in prostate cancer: a Delphi study across clinical scenarios.
Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo develop expert consensus recommendations in Spain for the management of biochemical recurrence (BCR) in prostate cancer across different clinical scenarios using a modified Delphi methodology, and to provide a multidisciplinary, evidence-based framework to inform clinical decision-making regarding definition, risk stratification, imaging, and treatment after radical prostatectomy (RP), radiotherapy (RT), and RP followed by salvage RT.
methodsA multidisciplinary scientific committee formulated 51 clinical statements based on a narrative literature review and expert experience. A panel of 49 specialists, including urologists, radiation oncologists, and nuclear medicine physicians, independently rated these statements through two rounds of an online Delphi survey.
resultsForty-two Spanish panelists completed both rounds. Consensus was reached for 38 of 51 statements (75%): 33 in the first round and 5 in the second. Key agreements included defining BCR after RP as a confirmed PSA rise ≥ 0.2 ng/mL; strong endorsement of next-generation imaging (NGI) for disease assessment, particularly in high-risk patients; and recommending salvage RT with or without androgen deprivation therapy (ADT) as the standard, reserving systemic therapy including androgen receptor pathway inhibitors (ARPI) for patients unsuitable for local salvage. The panel emphasized individualized ADT duration and risk-adapted imaging and treatment approaches. Additional areas of ongoing debate and future research needs were identified.
conclusionsThese expert-driven recommendations provide a structured clinical framework integrating current evidence and consensus guidance to optimize BCR management in prostate cancer. The findings support personalized decision-making and highlight areas requiring further prospective validation.
Indexed as
Identifiers
42471494What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.