Evidence map›Paper›PMID 42471454›Full record

ArticleScientific reports2026

The role of reduced sense of isolation in group-format PTSD treatment.

Diane Joss, Alexandra Comeau, Hanna Soumerai Rea, Adhithi Rajan, Martha Sweezy, Zev Schuman-Olivier

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Diane JossCenter for Mindfulness and Compassion, Cambridge Health Alliance, Malden, MA, USA. djoss@cha.harvard.edu.
Alexandra ComeauCenter for Mindfulness and Compassion, Cambridge Health Alliance, Malden, MA, USA.
Hanna Soumerai ReaCenter for Mindfulness and Compassion, Cambridge Health Alliance, Malden, MA, USA.
Adhithi RajanCenter for Mindfulness and Compassion, Cambridge Health Alliance, Malden, MA, USA.
Martha SweezyCenter for Mindfulness and Compassion, Cambridge Health Alliance, Malden, MA, USA.
Zev Schuman-OlivierCenter for Mindfulness and Compassion, Cambridge Health Alliance, Malden, MA, USA.

Funding

Neural mechanism of critical self-judgment as a trans-diagnostic therapeutic target: a secondary data analysis study from the RDoC perspectiveR03MH136402 · NIMH · CAMBRIDGE HEALTH ALLIANCE · PI JOSS, DIANE · 2024 to 2025
$164k
Foundation for Self Leadership R050120-CHANCCIH NIH HHS 3R01AT011002-04S1NIMH NIH HHS R03MH136402
6 · The paper itself

Abstract

With increasing application of group-based interventions for PTSD, more research is needed on what might contribute to the therapeutic effects of group-based interventions. This study conducted secondary analyses with data from a previous randomized controlled trial, which compared two manualized 16-week videoconferencing PTSD treatments in a hybrid format with 16 group sessions and 8 individual sessions. One treatment arm focused on cultivating inner compassion and understanding internal conflicts through a contemplative Internal Family Systems (IFS) approach, while the other treatment arm focused on watching nature videos and discussing nature's potential for stress reduction. The original RCT showed comparable effects on PTSD symptom reduction. Therefore, we conducted secondary analysis to elucidate whether both two group-based interventions, despite very different curriculum content, might have induced "reduced sense of isolation", which might be a shared therapeutic element in both treatment arms. Findings from Linear Mixed Effects model analysis and Variance Decomposition Analyses (VDA) showed significant reduction of sense of isolation at the end of both interventions, which was one of the major contributors to reduction of PTSD symptoms. Path analyses showed similarities between the two group-based treatment arms in which reduced sense of isolation was associated with improvements in self-judgment and emotion regulation, all of which contributed to PTSD symptom reduction. These findings may inspire and inform future PTSD treatment development to place more emphasis on reducing patients' sense of isolation.

Indexed as

Group therapyIsolationMindfulnessPsychoeducationStress

Identifiers

PMID42471454
PMCPMC13619444

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.