Evidence map›Paper›PMID 42470524›Full record

ArticleSleep & breathing = Schlaf & Atmung2026

Obstructive sleep apnea in patients with acute myocardial infarction: one-year follow-up study.

Justyna Tyfel-Paluszek, Aleksandra Mikunda, Aleksandra Kułaga, Łukasz Pominkiewicz, Jacek Łach, Robert Skomro, Wojciech Płazak

Abstract read
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Justyna Tyfel-PaluszekDepartment of Diagnostics, John Paul II Hospital, Kraków, Poland.
Aleksandra MikundaDepartment of Cardiac and Vascular Diseases, Jagiellonian University Medical College, John Paul II Hospital, Prądnicka 80, Kraków, 31-202, Poland.
Aleksandra KułagaDepartment of Cardiac and Vascular Diseases, Jagiellonian University Medical College, John Paul II Hospital, Prądnicka 80, Kraków, 31-202, Poland. aleksandra.kulaga@onet.pl.
Łukasz PominkiewiczDepartment of Coronary Artery Disease and Heart Failure, Jagiellonian University Medical College, John Paul II Hospital, Kraków, Poland.
Jacek ŁachDepartment of Cardiac and Vascular Diseases, Jagiellonian University Medical College, John Paul II Hospital, Prądnicka 80, Kraków, 31-202, Poland.
Robert SkomroDivision of Respirology, Critical Care and Sleep Medicine, College of Medicine, University of Saskatchewan, Saskatoon, Canada.
Wojciech PłazakDepartment of Cardiac and Vascular Diseases, Jagiellonian University Medical College, John Paul II Hospital, Prądnicka 80, Kraków, 31-202, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIM, MATERIALS AND

methodsObstructive sleep apnea (OSA) leads to organ ischemia, including that of the heart. The aim of this study was to assess the frequency of OSA by polygraphic examination in patients admitted with acute coronary syndrome, to evaluate the influence of OSA on echocardiographic findings and myocardial infarction markers and to describe the influence of CPAP treatment on OSA parameters and echocardiographic indices after myocardial infarction. We included 25 patients treated with primary coronary angioplasty, aged 60.3 ± 19.4 years, with a BMI of 32.2 ± 3.8.

resultsPolygraphy showed OSA in 18 (72%) patients, and in 12 (48%) severe OSA (AHI > 30) was diagnosed. OSA predominantly affected obese patients (BMI < 30, n = 13: AHI 23.2 ± 17.4, BMI ≥ 30, n = 12: AHI 55.5 ± 23.6, p < 0.000001). In patients with normal RV structure and function AHI was significantly lower compared to those with RV dysfunction. In patients without OSA, CKMB and troponin levels were significantly lower as compared to those with OSA: AHI < 15: CKMB 41.7 ± 40.7, Tn 0.84 ± 1.0; AHI≥15: CKMB 169.2 ± 112.4, Tn 4.77 ± 4.43; p = 0.04. CPAP therapy was started only in 9 (50%) patients with OSA due to low patient compliance. In patients treated with CPAP, the therapy resulted in a significant decrease in OSA indices (AHI dropped from 52.0 ± 18.6 to 5.0 ± 1.0; p = 0.001). The function of the RV, as measured by TAPSE, improved only in patients treated with CPAP (CPAP: from 20.5 ± 3.3 to 22.3 ± 2.3, p = 0.04; no CPAP: 22.3 ± 4.7 to 23.6 ± 1.8; p-ns).

conclusionsWe demonstrate a high prevalence of OSA in patients presenting with acute coronary syndrome. OSA influences RV enlargement and dysfunction, as well as CKMB and troponin levels during myocardial infarction. After myocardial infarction, RV function improves only in patients treated with CPAP.

Indexed as

Myocardial InfarctionSleep Apnea, ObstructiveAgedContinuous Positive Airway PressureEchocardiographyFemaleFollow-Up StudiesHumansMaleMiddle AgedPolysomnographyCPAPEechocardiographyMmyocardial infarctionObstructive sleep apnea

Identifiers

PMID42470524
PMCPMC13380547

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.