Evidence map›Paper›PMID 42470508›Full record

ArticleActa neurochirurgica2026

Long-term outcomes following primary resection of intraosseous meningiomas with concurrent cranioplasty: a population-based Swedish multicentre study.

Robert F Nilsson, Alba Corell, Emilia Muncan, Peter Lindvall, Rickard L Sjöberg, Richard Ågren, Bjartur Sæmundsson, Alexander Fletcher-Sandersjöö, Ulrik Birgersson, Jimmy Sundblom and 5 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neurochirurgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Robert F NilssonDepartment of Clinical Science - Neurosciences, Umeå University, 901 87, Umeå, Sweden. robert.nilsson@umu.se.ORCID 0000-0001-8007-455X
Alba CorellDepartment of Clinical Neuroscience, Institute of Neuroscience and Physiology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Emilia MuncanDepartment of Clinical Neuroscience, Institute of Neuroscience and Physiology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Peter LindvallDepartment of Clinical Science - Neurosciences, Umeå University, 901 87, Umeå, Sweden.
Rickard L SjöbergDepartment of Clinical Science - Neurosciences, Umeå University, 901 87, Umeå, Sweden.
Richard ÅgrenDepartment of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden.
Bjartur SæmundssonDepartment of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden.
Alexander Fletcher-SandersjööDepartment of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden.
Ulrik BirgerssonDepartment of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Jimmy SundblomDepartment of Medical Sciences, Section of Neurosurgery, Uppsala University, Uppsala, Sweden.
Mats RyttleforsDepartment of Medical Sciences, Section of Neurosurgery, Uppsala University, Uppsala, Sweden.
Göran HesselagerDepartment of Medical Sciences, Section of Neurosurgery, Uppsala University, Uppsala, Sweden.
David Fröjd ReveszDepartment of Medical Sciences, Section of Neurosurgery, Uppsala University, Uppsala, Sweden.
Teodor Svedung WettervikDepartment of Medical Sciences, Section of Neurosurgery, Uppsala University, Uppsala, Sweden.
Klas HolmgrenDepartment of Clinical Science - Neurosciences, Umeå University, 901 87, Umeå, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies on intraosseous meningiomas requiring cranioplasty have been scarce, and surgical outcomes thus remain poorly characterized. Using a population-based, multicentre cohort of patients who had undergone resection of intraosseous meningioma with concurrent cranioplasty, we aimed to establish long-term outcomes, as well as rates and predictors of complications and tumour recurrence.

methodAll patients who had undergone primary resection of an intraosseous meningioma with concurrent cranioplasty at four neurosurgical departments in Sweden between 2008 and 2022 were included. Data on patient demographics as well as tumour- and surgery-related data were collected retrospectively by scrutiny of medical records. Rates and predictors of surgical complications, and the composite outcome of tumour recurrence (including growth of residual tumour), were analysed using Cox regression.

resultsOf the 119 patients included, 16% experienced surgical complications requiring reoperation, 10% underwent implant explantation, and 31% developed tumour recurrence. Choice of implant material differed significantly across the participating centres but did not influence complication rates. Markers of biological aggressiveness were associated with an increased risk of surgical complications and tumour recurrence.

conclusionsSurgical complications and tumour recurrence are common following resection of intraosseous meningiomas with concurrent cranioplasty. Rather than the material used for cranial reconstruction, biological and anatomical tumour-related factors were the strongest predictors of adverse outcomes.

Indexed as

Meningeal NeoplasmsMeningiomaNeoplasm Recurrence, LocalNeurosurgical ProceduresPlastic Surgery ProceduresPostoperative ComplicationsAdultAgedFemaleHumansMaleMiddle AgedReoperationRetrospective StudiesSwedenTreatment OutcomeComplicationsCranioplastyIntraosseous meningiomaRecurrence

Identifiers

PMID42470508
PMCPMC13380628

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