Evidence map›Paper›PMID 42469888›Full record

ArticleAddiction science & clinical practice2026

OUTPACE Tobacco study protocol: a tobacco-free workplace program for dissemination and implementation in opioid use treatment programs in Texas.

Asfand B Moosa, Maggie Britton, Ammar D Siddiqi, Isabel Martinez Leal, Tzuan A Chen, Jennifer A Minnix, Maher A Karam-Hage, Paul M Cinciripini, Mhyank S Sekhar, Lorraine R Reitzel

Abstract read
In one paragraph

Article in Addiction science & clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Asfand B MoosaDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Houston, TX, 77030, USA.
Maggie BrittonDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Houston, TX, 77030, USA.
Ammar D SiddiqiDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Houston, TX, 77030, USA.
Isabel Martinez LealDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Houston, TX, 77030, USA.
Tzuan A ChenHEALTH Research Institute, University of Houston, 4349 Martin Luther King Blvd., Houston, TX, 77204, USA.
Jennifer A MinnixDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Houston, TX, 77030, USA.
Maher A Karam-HageDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Houston, TX, 77030, USA.
Paul M CinciripiniDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Houston, TX, 77030, USA.
Mhyank S SekharDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Houston, TX, 77030, USA.
Lorraine R ReitzelDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Houston, TX, 77030, USA. LReitzel@mdanderson.org.ORCID https://orcid.org/0000-0002-7165-5720

Funding

Cancer Prevention and Research Institute of Texas PP230078
6 · The paper itself

Abstract

backgroundTobacco use is exceedingly high among individuals with opioid addiction but not commonly addressed in opioid treatment programs (OTPs) due to a combination of pro-smoking social norms in OTPs, providers' lack of training, and the complex relationship between chronic pain and tobacco use. Comprehensive tobacco-free workplace programs in OTPs can address tobacco use with evidence-based policies and practices, but work is needed for adaptation to this specific setting. Project aims are to successfully implement, evaluate, and disseminate an adapted workplace intervention in OTPs.

methodsCalled [Opioid Use Treatment Programs Advancing Cessation Efforts] OUTPACE Tobacco, the intervention will include tobacco-free workplace policy implementation, clinical workflow changes, employee education, specialized provider training, and resource provision, including connection with treatment through the MD Anderson Tobacco Quitline at 2 Texas OTPs. A mixed method, hybrid effectiveness-implementation design will guide the work; the Exploration, Preparation, Implementation, and Sustainment framework will guide multiple implementation strategies aimed at integrating tobacco dependence care (e.g., screening, brief intervention, and referral for longer-term care) into the clinical workflow. DISCUSSION: Success will be measured by pragmatic implementation outcomes of acceptability, penetration, and sustainment; clinical outcomes (e.g., patient quit attempts, abstinence) will be assessed with patient/quitline records. Dissemination activities will include the distribution of an implementation guide and technical assistance provision to other OTPs. Innovation of this protocol includes novelty of application in OTPs and the use of a cancer center's quitline to deliver tobacco treatment. Results from OUTPACE Tobacco will inform tobacco control implementation science while providing practical guidance about integrating best practice recommendations in treating tobacco use disorder in OTPs; ultimately, similar implementations could mitigate the tobacco use disparities experienced by OTP patients.

trial registrationNot applicable.

Indexed as

Opioid-Related DisordersSmoking CessationTobacco Use DisorderWorkplaceHumansTexasCancer preventionCessationImplementation scienceInterventionMixed-methodsOpioidsTobaccoTobacco-free workplace program

Identifiers

PMID42469888
PMCPMC13670504

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.