Evidence map›Paper›PMID 42469708›Full record

ArticleBMC psychiatry2026

Prevalence of severe neurobehavioral disorders among adults with traumatic brain injury at Mbarara Regional Referral Hospital in southwestern Uganda.

Bernard Sserwanga, Joseph Kirabira, David Kitya, Scholastic Ashaba, Christine Etoko Atala, Godfrey Zari Rukundo, Samuel Maling

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Article in BMC psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Bernard SserwangaDepartment of Psychiatry, Mbarara University of Science and Technology, Mbarara, Uganda.
Joseph KirabiraDepartment of Psychiatry, Busitema University - Mbale Campus, Mbale, Uganda. kirabirajoseph64@gmail.com.
David KityaDepartment of Surgery, Mbarara University of Science and Technology, Mbarara, Uganda.
Scholastic AshabaDepartment of Psychiatry, Mbarara University of Science and Technology, Mbarara, Uganda.
Christine Etoko AtalaDepartment of Anaesthesia and Critical Care, Lira Regional Referral Hospital, Lira, Uganda.
Godfrey Zari RukundoDepartment of Psychiatry and Neurobehavioral Sciences, McMaster University, Hamilton, ON, Canada.
Samuel MalingDepartment of Psychiatry, Mbarara University of Science and Technology, Mbarara, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraumatic brain injuries (TBI) are frequently accompanied by neuropsychiatric disturbances. Failure to quickly assess and manage these disturbances results in neurobehavioral syndromes, with deleterious effects on recovery and rehabilitation outcomes. This study determined the prevalence and predictors of severe neurobehavioral disorders among patients with TBI at Mbarara Regional Referral Hospital in southwestern Uganda.

methodsIn this cross-sectional study, we enrolled participants aged 18 years or older who were able to communicate meaningfully and had been discharged by the neurosurgical team. We obtained information on socio-demographic characteristics, alcohol use, length of stay in the hospital, Glasgow Coma Scale (GCS) score at admission, clinical diagnosis, treatments given, and investigations, including brain computed tomography scans. Neurobehavioral disorders were determined using the Neurobehavioral Rating Scale. Predictors of neurobehavioral disorders were determined using logistic regression.

resultsOf the 196 participants, 139 (70.8%) were male. The Median age (interquartile range (IQR)) was 30 (23-40) years, and the median length of hospital stay (IQR) was 7 (5-10) days; median GCS (IQR) was 13/15 (10/15 - 14/15), and the prevalence of neurobehavioral disorders was 55.4%. Factors associated with neurobehavioral disorders were age > 35 years (odds ratio (O.R) = 4.7 (1.6-13.5) and > 7 days of hospital admission (O.R = 4.3 (1.4-13.0). Having a GCS score of 13-15 at admission was protective (O.R = 0.13 (0.02-0.85) against neurobehavioral disorders compared to a score of < 8.

conclusionThe high prevalence of neurobehavioral disorders among individuals with a history of TBI at the point of discharge from the hospital may affect post-discharge care. Hence, there is a need to meticulously assess and address these challenges early to improve the long-term treatment outcomes of TBI. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Brain Injuries, TraumaticMental DisordersAdultCross-Sectional StudiesFemaleGlasgow Coma ScaleHumansLength of StayMaleMiddle AgedPrevalenceReferral and ConsultationUgandaYoung AdultBrain injuryNeurobehavioral disordersRecoveryRural UgandaTrauma

Identifiers

PMID42469708
PMCPMC13670713

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.