Evidence map›Paper›PMID 42469651›Full record

ArticleBMC plant biology2026

Regional variation in total flavonoid content and antioxidant activity of Artemisia dracunculus L. in Xinjiang, China.

Yu Zhang, Yingxuan Geng, Xiaoli Ma, Zhangjian Huang, Hailiqian Taoerdahong, Junmin Chang

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Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Yu Zhang *Key Laboratory of Active Components of Xinjiang Natural Medicine and Drug Release Technology, No. 567 Shangde North Road, Shuimogou District, Urumqi, Xinjiang Uygur Autonomous Region, 830011, China.
Yingxuan Geng *College of Basic Medical Sciences, Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, 830011, China.
Xiaoli MaCollege of Pharmacy, Xinjiang Medical University, No. 567 Shangde North Road, Shuimogou District, Urumqi, Xinjiang Uygur Autonomous Region, 830011, China.
Zhangjian HuangCollege of Pharmacy, Xinjiang Medical University, No. 567 Shangde North Road, Shuimogou District, Urumqi, Xinjiang Uygur Autonomous Region, 830011, China. huangzjxj@126.com.
Hailiqian TaoerdahongCollege of Traditional Chinese Medicine, Xinjiang Medical University,, No. 567 Shangde North Road, Shuimogou District, Urumqi, Xinjiang Uygur Autonomous Region, 830011, China. hlqtedh@126.com.
Junmin ChangKey Laboratory of Active Components of Xinjiang Natural Medicine and Drug Release Technology, No. 567 Shangde North Road, Shuimogou District, Urumqi, Xinjiang Uygur Autonomous Region, 830011, China. changjunmincjm@126.com.

Funding

Key Laboratory of Active Components of Xinjiang Natural Medicine and Drug Release Technology 2024XJTRY05Undergraduate Innovation and Entrepreneurship Training Program of Xinjiang Uygur Autonomous Region S202510760076Youth Fund Project of Xinjiang Medical University 2024XYZR10
6 · The paper itself

Abstract

backgroundArtemisia dracunculus L. (A. dracunculus) is a distinctive plant resource in Xinjiang, possesses both medicinal and culinary value, with distinct regional characteristics.

methodsIn this study, total flavonoids extracted from A. dracunculus (TFAD) were obtained using a reflux method, with extraction parameters optimized through single-factor experimental design. Ultraviolet-visible spectrophotometry was used for both qualitative and quantitative assessment of TFAD. Samples collected from Jimusaer, Hami, and Tacheng in Xinjiang were analyzed for total flavonoid content and antioxidant activity.

resultsThe optimized extraction conditions included 50% ethanol as the solvent, a solid-to-liquid ratio of 1:30, an extraction temperature of 80 °C, and a duration of 8 h. Under these conditions, the TFAD content in samples from Jimusaer, Hami, and Tacheng was 107.0146 ± 1.4986, 111.9548 ± 1.6136, and 124.8996 ± 1.3801 mg g⁻¹, respectively. Statistically significant regional differences were observed (p < 0.01), with the highest flavonoid concentration found in samples from Tacheng. Antioxidant activities of TFAD from the three regions were assessed using in vitro free radical scavenging assays, with ascorbic acid (AA) serving as the positive control. TFAD extracted from Jimusaer exhibited the strongest antioxidant capacity, with IC₅₀ values of 31.31 ± 1.19 and 114.04 ± 5.56 µg mL⁻¹ against DPPH and ABTS⁺· radicals, respectively, compared with 7.25 ± 0.56 and 154.18 ± 9.54 µg mL⁻¹ for AA.

conclusionThese results suggest that TFAD from the Jimusaer region demonstrates superior antioxidant activity, providing a basis for further exploration and potential utilization of A. dracunculus as a functional resource in Xinjiang.

Indexed as

AntioxidantsArtemisiaFlavonoidsBiphenyl CompoundsChinaPicrates1,1-diphenyl-2-picrylhydrazylAntioxidantsBiphenyl CompoundsFlavonoidsPicratesA. dracunculusAntioxidant activityTotal flavonoids

Identifiers

PMID42469651
PMCPMC13591882

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