Evidence map›Paper›PMID 42469628›Full record

ArticleBMC genomic data2026

Draft genome assembly of hyper citric acid-producing Aspergillus niger mutant strain developed through gamma radiation bombardment.

Ambreen Latif, Hazrat Ali, Muhammad Salman Haider, Muhammad Bilal Khan Niazi, Noor Hassan, Asad Ali

Abstract read
In one paragraph

Article in BMC genomic data, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ambreen LatifNational Institute for Biotechnology and Genetic Engineering-College (NIBGE-C), Pakistan Institute of Engineering and Applied Sciences (PIEAS), Faisalabad, Pakistan.
Hazrat AliNational Institute for Biotechnology and Genetic Engineering-College (NIBGE-C), Pakistan Institute of Engineering and Applied Sciences (PIEAS), Faisalabad, Pakistan. alibiotechnologist@gmail.com.
Muhammad Salman HaiderDepartment of Chemical Engineering, School of Chemical and Materials Engineering, National University of Sciences and Technology, Islamabad, 44000 H-12, Pakistan. salman.haider@scme.nust.edu.pk.
Muhammad Bilal Khan NiaziDepartment of Chemical Engineering, King Fahd University of Petroleum and Minerals (KFUPM), Dhahran, Saudi Arabia.
Noor HassanNational Institute for Biotechnology and Genetic Engineering-College (NIBGE-C), Pakistan Institute of Engineering and Applied Sciences (PIEAS), Faisalabad, Pakistan.
Asad AliNational Institute for Biotechnology and Genetic Engineering-College (NIBGE-C), Pakistan Institute of Engineering and Applied Sciences (PIEAS), Faisalabad, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAspergillus niger is a renowned filamentous fungus with extensive industrial and biotechnological applications. A. niger is widely used to produce diverse organic acids, enzymes, and other value-added metabolites. Although strain-specific metabolic capabilities have been widely applied in industry, the genomic foundations of these capabilities have not yet been fully characterized. Here, we have described the isolation and provided the draft genome sequence of A. niger strain AN-L103_M1 to further study the genetic determinants of primary and secondary metabolism, given its metabolic versatility and great potential in biotechnology. This A. niger strain was developed through gamma radiation bombardment, and subsequently, all the mutants were screened through various steps for hyperproduction of citric acid. This genome sequence provided valuable information for further functional genomics and strain-improvement research. DATA DESCRIPTION: The A. niger strain was obtained through gamma radiation bombardment. After gamma radiation bombardment of the A. niger culture, it was subjected to various screening steps to achieve hyperproduction of citric acid. These experiments were performed in the Industrial Biotechnology Division, National Institute for Biotechnology and Genetic Engineering, Faisalabad, Pakistan. The mycotoxin production potential of this mutant strain was assessed using LC-MS analysis, which detected no mycotoxins.

Indexed as

Aspergillus nigerCitric AcidGamma RaysGenome, FungalMutationCitric AcidAspergillus nigerCitric acidGenome assembly

Identifiers

PMID42469628
PMCPMC13670436

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.