Evidence map›Paper›PMID 42467964›Full record

ArticleJMIR research protocols2026

Evaluating the Outcomes of the Capacity-Building Support From a Collaborative Network of Implementation Science Technical Assistance Hubs: Protocol for a Mixed Methods Evaluation.

Sung-Jae Lee, Hannah Mestel, Carolyn M Audet, Bijal Balasubramanian, Nanette Benbow, Shruti Chandra, Carrie Geremia, Raul U Hernandez-Ramirez, Joyce L Jones, Olivia Keatley and 11 more

Abstract read
In one paragraph

Article in JMIR research protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Sung-Jae LeePsychiatry and Biobehavioral Sciences, David Geffen School of Medicine, Division of Population Behavioral Health, University of California, Los Angeles, Los Angeles, CA, United States.ORCID 0000-0002-7924-7430
Hannah Mestel *Yale School of Public Health, Yale University, New Haven, CT, United States.ORCID 0009-0007-3249-3072
Carolyn M Audet *Department of Health Policy, Vanderbilt University, Nashville, TN, United States.ORCID 0000-0002-4715-1346
Bijal Balasubramanian *UTHealth Houston Institute for Implementation Science, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX, United States.ORCID 0000-0003-2844-9048
Nanette Benbow *Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Impact Institute, Northwestern University, Chicago, IL, United States.ORCID 0000-0001-6715-1530
Shruti ChandraImpact Institute, Northwestern University, Chicago, IL, United States.ORCID 0000-0003-1818-5042
Carrie GeremiaAltman Clinical and Translational Research Institute Dissemination and Implementation Science Center, Herbert Wertheim School of Public Health and Human Longevisty Science, University of California San Diego, La Jolla, CA, United States.ORCID 0000-0001-9159-8172
Raul U Hernandez-RamirezYale School of Public Health, Yale University, New Haven, CT, United States.ORCID 0000-0001-8272-1474
Joyce L Jones *Department of Medicine, Division of Infectious Diseases, Johns Hopkins Medicine, Baltimore, MD, United States.ORCID 0000-0001-5882-0907
Olivia KeatleyEmory Center for AIDS Research, Emory University, Atlanta, GA, United States.ORCID 0009-0005-1156-1430
Christopher Kemp *Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.ORCID 0000-0003-1231-1546
Christine M Khosropour *Department of Epidemiology, University of Washington, Seattle, WA, United States.ORCID 0000-0002-9743-0829
Robin Gaines Lanzi *Department of Health Behavior, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, United States.ORCID 0000-0002-5013-4141
Mary-Louise E Millett *UTHealth Houston Institute for Implementation Science, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX, United States.ORCID 0000-0002-6599-5622
Alexandra B Morshed *Behavioral, Social, and Health Education Sciences Department, Rollins School of Public Health, Emory University, Atlanta, GA, United States.ORCID 0000-0001-9960-0409
April C Pettit *Vanderbilt University Medical Center, Nashville, TN, United States.ORCID 0000-0001-8832-0866
Alec PowersImpact Institute, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-4037-5320
Borsika A Rabin *Altman Clinical and Translational Research Institute Dissemination and Implementation Science Center, Herbert Wertheim School of Public Health and Human Longevisty Science, University of California San Diego, La Jolla, CA, United States.ORCID 0000-0001-9837-7866
Jessica M Sales *Behavioral, Social, and Health Education Sciences Department, Rollins School of Public Health, Emory University, Atlanta, GA, United States.ORCID 0000-0002-1571-8192
Nicole A Stadnick *Department of Psychiatry, Altman Clinical and Translational Research Institute Dissemination and Implementation Science Center, San Diego HIV Implementation Science Center, Child and Adolescent Services Research Center, University of California San Diego, La Jolla, CA, United States.ORCID 0000-0001-6520-2920
Debbie Humphries *Yale School of Public Health, Yale University, New Haven, CT, United States.ORCID 0000-0002-5979-3717

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI CONNIE L CELUM · 1988 to 2026
$104.9M
Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Paul A. Goepfert · 1988 to 2026
$84.1M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUSAN JANET LITTLE · 1994 to 2026
$78.4M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Anna Palmer Durbin · 2012 to 2026
$67.0M
UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Sung-Jae Lee · 1997 to 2026
$53.5M
Using Coincidence Analysis to Investigate Factors Affecting PrEP Initiation and Continuation in Southern ending the Epidemic CountiesP30MH062294 · NIMH · YALE UNIVERSITY · PI Trace S Kershaw · 2001 to 2026
$48.5M
Virology and Immunology Technology CoreP30AI117943 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Sahera Dirajlal-Fargo · 2015 to 2026
$38.4M
Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John Koethe · 2015 to 2026
$27.5M
Texas Developmental Center for AIDS ResearchP30AI161943 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI RICE, ANDREW P · 2021 to 2025
$8.3M
NIAID NIH HHS P30 AI027757NIAID NIH HHS P30 AI027767NIAID NIH HHS P30 AI036214NIAID NIH HHS P30 AI050409NIAID NIH HHS P30 AI094189NIAID NIH HHS P30 AI110527NIAID NIH HHS P30 AI117943NIAID NIH HHS P30 AI161943NIMH NIH HHS P30 MH058107NIMH NIH HHS P30 MH062294
6 · The paper itself

Abstract

backgroundImplementation science (IS) plays a critical role in translating research into real-world health outcomes. Few studies have evaluated models that provide technical assistance and other resources to build IS capacity. The Coordinating and Capacity-Building Hubs to Enhance the Science of HIV Implementation Research (CHESHIRE) network supports US-based HIV research awardees participating in the Ending the HIV Epidemic in the US (EHE) initiative.

objectiveThe objective of this study is to describe the evaluation protocol for CHESHIRE and assess the effect of the implementation of hub technical assistance activities on EHE-funded research team outcomes, including IS competencies, scientific collaboration, and research productivity.

methodsThis protocol describes a mixed methods evaluation using qualitative interviews with EHE project leads (n=36); social network analysis of CHESHIRE-affiliated researchers and hub members (n=265); and secondary data analysis of National Institutes of Health (NIH) RePORTER, PubMed, and NIH Implementation Science Coordination Initiative EHE Project Final Progress Report Survey data (n=248). We will use descriptive analyses, network metrics, and thematic coding to describe outcomes following CHESHIRE implementation, including IS competencies, interinstitutional partnerships, and research productivity.

resultsCHESHIRE coordinating center and hub activities were funded through NIH Center for AIDS Research and AIDS Research Center supplements beginning in 2019, with hubs funded between 2019 and 2024. Available survey data include EHE projects that completed the EHE Project Final Progress Report Survey between August 2021 and February 2025. As of January 2026, we have completed enrollment, with 265 network members in the final recruiting list. Data abstraction and analysis of the evaluation components are ongoing. Publication of findings is anticipated for December 2026. Evaluation findings will be disseminated after completion of data analysis. The findings will provide insights on whether structured IS support through CHESHIRE increases researchers' IS competencies, interinstitutional partnerships, and research productivity.

conclusionsThis evaluation will provide empirical evidence to guide the development and optimization of technical assistance hubs in public health research and inform their future evaluation of hub-based IS capacity-building models. Findings will inform strategies to optimize IS capacity building and accelerate the translation of evidence-based interventions into practice, especially in HIV prevention and treatment. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/91374.

Indexed as

Capacity BuildingHIV InfectionsImplementation ScienceCooperative BehaviorHumansProgram EvaluationQualitative ResearchUnited Statescapacity buildingEnding the HIV Epidemic in the USHIVimplementation scienceinterviewsmixed methods evaluationsocial network analysis

Identifiers

PMID42467964
PMCPMC13428205

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.