Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
15 authors.
Hongyang XuAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.ORCID 0000-0001-8878-0600
Shylesh BhaskaranAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.ORCID 0000-0002-0651-2299
Jacob BrownAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.ORCID 0000-0003-0912-7924
Luis Gustavo Oliveira de SousaAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.ORCID 0000-0003-1013-2595
Constantin GeorgescuAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.ORCID 0000-0003-1389-8342
Elizabeth DugganAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.ORCID 0009-0001-9072-2773
Kara KneuperAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.ORCID 0009-0000-5063-2362
Ashley BellAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Jessica ThomasonAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Andy Gamez-RicoAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Bo HagyAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Victoria TyrrellSystems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom.ORCID 0000-0002-2987-118X
Valerie B O'DonnellSystems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom.ORCID 0000-0003-4089-8460
Kenneth HumphriesAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.ORCID 0000-0002-6167-3175
Holly Van RemmenAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.ORCID 0000-0003-0883-0642
Funding
A novel role for oxidized lipid mediators as effectors of muscle atrophy and weakness in agingR01AG077812 · NIA · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI Kenneth M Humphries · 2022 to 2026
$2.8M
BLRD VA IK6 BX005234NIA NIH HHS R01 AG077812
6 · The paper itself
Abstract
Sarcopenia, the age-related loss of skeletal muscle mass and strength, is a major cause of frailty and disability, with neuromuscular denervation as a key contributor. Bioactive lipid mediators, including lipid hydroperoxides and oxylipins, contribute to denervation-induced muscle atrophy and dysfunction. Here, we identify calcium-independent phospholipase A
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.