Evidence map›Paper›PMID 42467732›Full record

SynthesisAmerican journal of speech-language pathology2026

Understanding Right-Hemisphere Language Disorders Through a Half-Century of Research: A Systematic Review.

Margaret Lehman Blake, Perrine Ferré, Laura Murray, Ronelle Hewetson, Melissa Johnson, Alexandra Zezinka Durfee, Jamila Minga, Shannon M Sheppard, Amanda Love

Abstract readSystematic Review
In one paragraph

Synthesis in American journal of speech-language pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Margaret Lehman BlakeCommunication Sciences and Disorders, University of Houston, TX.ORCID 0000-0002-6096-8174
Perrine FerréSchool of Physical & Occupational Therapy, McGill University, Montreal, Quebec, Canada.
Laura MurraySchool of Communication Sciences and Disorders, Western University, London, Ontario, Canada.ORCID 0000-0002-7773-1843
Ronelle HewetsonSchool of Allied Health, Sport and Social Work, Griffith University, Gold Coast, Queensland, Australia.ORCID 0000-0003-1872-9943
Melissa JohnsonCommunication Sciences and Disorders Department, Nazareth University, Rochester, NY.ORCID 0000-0002-5546-1395
Alexandra Zezinka DurfeeDepartment of Speech-Language Pathology & Audiology, Towson University, MD.ORCID 0000-0003-2067-8217
Jamila MingaDepartment of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, NC.ORCID 0000-0002-2301-8954
Shannon M SheppardDepartment of Speech & Hearing Sciences, University of Washington, Seattle.
Amanda LoveSchool of Allied Health, Sport and Social Work, Griffith University, Gold Coast, Queensland, Australia.

Funding

RHDBank Database DevelopmentR01DC008524 · NIDCD · CARNEGIE-MELLON UNIVERSITY · PI BRIAN MACWHINNEY · 2007 to 2026
$7.0M
Recovery of language and theory of mind after strokeR01DC019828 · NIDCD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MARGARET LEHMAN BLAKE, Tatiana Tamara Schnur · 2022 to 2026
$3.5M
Neuroanatomic Correlates of Language Production Characteristics After Right Hemisphere StrokeK23DC020236 · NIDCD · DUKE UNIVERSITY · PI Jamila Minga · 2023 to 2026
$751k
NIDCD NIH HHS K23 DC020236NIDCD NIH HHS R01 DC008524NIDCD NIH HHS R01 DC019828
6 · The paper itself

Abstract

purposeLanguage deficits affecting multiple domains (e.g., semantics, pragmatics) have been reported after right-hemisphere (RH) stroke. The goal of the current study was to summarize the existing knowledge within the apragmatism framework.

methodA Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-guided systematic review of 55 years of research was conducted. Data were extracted to describe study characteristics, along with linguistic and extralinguistic apragmatism components.

resultsAfter content and quality reviews, 233 articles were included. Data were reported for over 4,300 participants with RH stroke. Methodological weaknesses included poor participant descriptions and use of experimental versus standardized/published assessments. Linguistic comprehension deficits were apparent at the word, sentence, and discourse levels, primarily in figurative language, inferencing, use of context, and humor. Linguistic production deficits at all three levels occurred particularly with less-structured elicitation tasks. Specifically for discourse, deficits affected coherence, cohesion, intended meaning, and emotional processing. Extralinguistic deficits consistently affected comprehension and production of facial expression; few studies examined other nonverbal communication cues.

conclusionsLanguage deficits at the word, sentence, and discourse levels can occur after RH stroke: Linguistic and extralinguistic apragmatism predominantly affect figurative language, inferencing, emotion, and intended meaning. Weaknesses in research methodology impede clear understanding of the language challenges experienced by this population.

Indexed as

Functional LateralityLanguage DisordersStrokeComprehensionHumansLinguistics

Identifiers

PMID42467732
PMCPMC13576688

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.