Evidence map›Paper›PMID 42467608›Full record

ArticlePloS one2026

Automated CT dataset generation as a novel concept for verification of backshape-to-spine approach and Cobb Angle Estimation.

David Fräulin, Irina Sidorenko, Renée Lampe

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Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

David FräulinDepartment of Clinical Medicine, Center for Digital Health and Technology, Orthopedic Department, Research Unit for Paediatric Neuroorthopedics and Cerebral Palsy of the Buhl-Strohmaier Foundation, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.ORCID https://orcid.org/0009-0002-6228-9148
Irina SidorenkoDepartment of Clinical Medicine, Center for Digital Health and Technology, Orthopedic Department, Research Unit for Paediatric Neuroorthopedics and Cerebral Palsy of the Buhl-Strohmaier Foundation, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Renée LampeDepartment of Clinical Medicine, Center for Digital Health and Technology, Orthopedic Department, Research Unit for Paediatric Neuroorthopedics and Cerebral Palsy of the Buhl-Strohmaier Foundation, Markus Würth Professorship, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.ORCID https://orcid.org/0000-0002-1016-0249

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdolescent idiopathic scoliosis is a condition that affects up to 3% of adolescents. Although radiographic imaging is the gold standard for diagnosis and monitoring, repeated exposure to ionizing radiation poses significant health risks. Alternative methods, such as estimating spinal alignment and Cobb angle from back surface topography, have been proposed to mitigate these risks. However, validation of these methods is challenging because traditional datasets combine back surface scans and radiographs acquired at different times and in different postures. This introduces technique-dependent errors and makes it difficult to determine whether observed discrepancies stem from the method itself or from inconsistencies in the validation dataset. As a result, this uncertainty in methods accuracy arising from verification errors, limits these alternatives to complementary roles rather than establishing them as reliable diagnostic tools.

methodsTo address this limitation, we introduce a fully automated approach for generating verification datasets directly from computed tomography images. This approach enables precise and synchronized extraction of both external back surface and internal spinal structures, thereby eliminating posture-related discrepancies present in commonly used datasets. We assess the utility of our method through a two-step validation: first, by comparing automatically extracted parameters with manual measurements; and second, by comparing the results of an established surface topography method applied to our dataset with reported values from the literature.

resultsOur findings suggest that this automatically extracted CT dataset serves as a suitable reference standard for the verification and comparison of surface topography approaches.

conclusionThis work provides a robust framework for future verification studies of different surface topography methods and may facilitate the development of non-radiographic techniques for scoliosis assessment, thereby reducing reliance on ionizing radiation in clinical practice.

Indexed as

ScoliosisSpineTomography, X-Ray ComputedAdolescentHumansImage Processing, Computer-Assisted

Identifiers

PMID42467608
PMCPMC13379039

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.