Evidence map›Paper›PMID 42467473›Full record

ArticleThe Journal of general virology2026

Human pegivirus, Toscana virus and herpesviruses identified in cerebrospinal fluid from adults with unexplained neurologic disease, Spain, 2022-2023.

Ana Donoso, Ana Belén Pérez, Marcos Lopez-Dosil, Ana Vázquez, Fabiana Gámbaro, María Paz Sánchez-Seco, Luis Martinez-Martinez, Maria Cabrerizo, David Tarragó, Maria Dolores Fernandez-Garcia

Abstract readMulticenter Study
In one paragraph

Article in The Journal of general virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ana DonosoCentro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Ana Belén PérezHospital Universitario Reina Sofia, Córdoba, Spain.
Marcos Lopez-DosilHospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain.
Ana VázquezCentro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Fabiana GámbaroSpatial Epidemiology Lab (SpELL), Université Libre de Bruxelles, CP 264/03 Avenue F. Roosevelt 50, Brussels 1050, Belgium.
María Paz Sánchez-SecoCentro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Luis Martinez-MartinezHospital Universitario Reina Sofia, Córdoba, Spain.
Maria CabrerizoCentro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
David TarragóCentro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Maria Dolores Fernandez-GarciaCentro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral central nervous system (CNS) infections in adults frequently remain unresolved after routine diagnostic testing. We applied probe-based viral metagenomic next-generation sequencing (vmNGS) to cerebrospinal fluid samples from adults with suspected CNS infection and negative conventional diagnostics in a retrospective multicentre study conducted in Spain between 2022 and 2023. Among 40 idiopathic cases, vmNGS detected viral sequences in 6 patients without evidence of coinfection: human pegivirus (HPgV,

Indexed as

Cerebrospinal FluidFlaviviridae InfectionsHerpesviridaeNervous System DiseasesPegivirusSandfly fever Naples virusAdultAgedFemaleHigh-Throughput Nucleotide SequencingHumansMaleMiddle AgedRetrospective StudiesSpaincentral nervous system infectionsherpesviruseshuman pegivirusToscana virusviral metagenomics

Identifiers

PMID42467473
PMCPMC13379243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.