Evidence map›Paper›PMID 42467146›Full record

ArticleEnvironmental science and pollution research international2026

Genotoxic effects of association of the biogenic amines cadaverine and putrescine on the Xenopus tropicalis fibroblast cell line.

Letícia Rocha Gonçalves, Letícia Tamborlin, Augusto Ducati Luchessi, Nicolas Pollet, Maria Aparecida Marin-Morales

Abstract read
In one paragraph

Article in Environmental science and pollution research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Letícia Rocha GonçalvesDepartment of General and Applied Biology, Institute of Biosciences, São Paulo State University Júlio de Mesquita Filho, Av. 24-A 1515, Rio Claro, SP, 13506-900, Brazil.
Letícia TamborlinDepartment of General and Applied Biology, Institute of Biosciences, São Paulo State University Júlio de Mesquita Filho, Av. 24-A 1515, Rio Claro, SP, 13506-900, Brazil.
Augusto Ducati LuchessiDepartment of General and Applied Biology, Institute of Biosciences, São Paulo State University Júlio de Mesquita Filho, Av. 24-A 1515, Rio Claro, SP, 13506-900, Brazil.
Nicolas PolletUMR Évolution, Génomes, Comportement et Écologie, Université Paris-Saclay, CNRS, IRD, 91198, Gif-Sur-Yvette, France.
Maria Aparecida Marin-MoralesDepartment of General and Applied Biology, Institute of Biosciences, São Paulo State University Júlio de Mesquita Filho, Av. 24-A 1515, Rio Claro, SP, 13506-900, Brazil. marin.morales@unesp.br.ORCID http://orcid.org/0000-0003-3890-0648

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 306062/2019-4Coordenação de Aperfeiçoamento de Pessoal de Nível Superior # 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/21914-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/06951-3
6 · The paper itself

Abstract

During cadaveric decomposition, necro-leachate is released into the surrounding environment, containing organic compounds such as the biogenic amines cadaverine (CAD) and putrescine (PUT). In this study, we performed the first integrated assessment of the genotoxic effects of CAD and PUT combinations at different concentrations (CAD: 0.3 × 10⁻

Indexed as

CadaverineFibroblastsPutrescineAnimalsApoptosisCell LineComet AssayDNA DamageMicronucleus TestsXenopusCadaverinePutrescineAmphibian cell lineCell deathCemetery pollutionDNA damageEnvironmental impactNecro-leachate

Identifiers

PMID42467146
PMCPMC13424187

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.