Evidence map›Paper›PMID 42467095›Full record

ArticleJournal of mathematical biology2026

Hyper-exponential growth in an epidemic model: some explicit solutions and their significance.

John M Halley

Abstract read
In one paragraph

Article in Journal of mathematical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

John M HalleyLaboratory of Ecology, Department of Biological Applications and Technology, University of Ioannina, 45110, Ioannina, Greece. jhalley@uoi.gr.ORCID http://orcid.org/0000-0001-9759-6792

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic highlighted the ability of epidemics to evolve through the emergence of successive strains of greater infectiousness, which prompted the insight that hyper-exponential growth (HEG) can arise in the development of an epidemic. The phenomenon of HEG has intrigued many researchers, because of some radical differences from exponential growth such as the finite-time singularity. However, the actual mechanism of HEG was usually hidden or needed to be added phenomenologically. Thus, there was little insight into how constraints would be triggered. In this study, we explore an SIR model with evolving parameters leading to a discrete sequence of variants. This allows us to consider the HEG phenomenon in greater depth and with greater mathematical rigour. The model yields a mechanistic description of what happens at the collapse of HEG. The model also yields closed expressions for important features, such as the critical time to the singularity, in terms of basic demographic parameters. Our analysis flags a few important issues needing further research, such as the stochastic character of the emergence of variants. Greater understanding of the HEG process will yield dividends in other fields, since modern societies exhibit HEG at several levels, such as human population growth, economic indicators and technological innovation. For this reason, more research on HEG remains imperative, especially on HEG in the presence of limited resources.

Indexed as

COVID-19Epidemiological ModelsModels, BiologicalSARS-CoV-2Basic Reproduction NumberComputer SimulationEpidemicsHumansMathematical ConceptsPandemicsStochastic ProcessesFinite-time singularityHyper-exponential growthMutationSIR modelSuper-exponential growthTransmission coefficient

Identifiers

PMID42467095
PMCPMC13379400

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.