ArticleJournal of the International Association of Providers of AIDS Care
Factors Associated With Viral Load Suppression Among Adults on Dolutegravir and Efavirenz: A Cross-Sectional Study in Papua, Indonesia.
Article in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
PurposeThis study aimed to investigate factors associated with viral load (VL) suppression among adults on Dolutegravir (DTG) and Efavirenz EFV)-based regimens antiretroviral therapy (ART) in Papua, Indonesia.MethodsA cross-sectional study was conducted in a referral hospital, Papua Province.ResultsA total of 300 PLWH had either EFV-based regimens (50%) or DTG-based regimens (50%) equally. The majority PLWH had unsuppressed VL (70%). The multivariate analysis among PLWH with EFV-based regimens showed that having TB (AOR = 5.74; 95% CI = 2.30-14.31) was significantly associated with unsuppressed VL. Being better quality of mental health (MCS) (AOR=0.95; 95% CI =0.92-0.99) decreased the likelihood of unsuppressed VL. Moreover, those with DTG-based regimens TB (AOR = 2.60; 95% CI = 1.06-6.37) was significantly associated with unsuppressed VL. Being better quality of MCS (AOR=0.97; 95% CI =0.94-1.00), and those with high necessity of ART (AOR = 0.83; 95% CI = 0.72-0.95) decreased likelihood of unsuppressed VL.ConclusionsThere is a need to raise awareness about increasing the number of PLWH with VL suppression, particularly those with DTG-based regimens. This study suggests that during the launch of new ART, healthcare providers must be educated to increase their knowledge of the new therapy.
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