ArticleJACC. Case reports2026
Transcatheter Aortic Valve Implantation for Native Aortic Regurgitation After Healed Infective Endocarditis.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Aortic Regurgitation in Challenging Anatomy: Expanding the Possibilities of Transcatheter Valve Therapy.JACC. Case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere native aortic regurgitation due to cusp perforation after healed infective endocarditis presents challenges for transcatheter aortic valve implantation (TAVI), particularly without annular calcification. CASE SUMMARY: A 46-year-old patient with healed infective endocarditis presented with severe eccentric aortic regurgitation due to perforation of the left coronary cusp. Given prohibitive surgical risk, transfemoral TAVI using the JenaValve Trilogy system was performed. Controlled deflection and rotational repositioning enabled coaxial alignment of the valve above the native cusps prior to deployment, resulting in no paravalvular leak and excellent hemodynamic outcome. DISCUSSION: This case highlights the technical challenges of TAVI in aortic regurgitation with cusp perforation and demonstrates how leaflet-locator anchoring, delivery system deflection, and multimodality imaging enable safe and effective valve positioning. TAKE-HOME MESSAGE: Cusp perforation may cause locator misengagement during TAVI; controlled deflection and repositioning are critical to achieve safe, stable deployment.
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